Lineage for d1hcfa_ (1hcf A:)

  1. Root: SCOPe 2.06
  2. 2256768Class g: Small proteins [56992] (94 folds)
  3. 2260390Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2260391Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2260595Family g.17.1.3: Neurotrophin [57520] (5 proteins)
    automatically mapped to Pfam PF00243
  6. 2260625Protein Neurotrophin 4, NT4 [57523] (1 species)
  7. 2260626Species Human (Homo sapiens) [TaxId:9606] [57524] (3 PDB entries)
  8. 2260628Domain d1hcfa_: 1hcf A: [65788]
    Other proteins in same PDB: d1hcfx_, d1hcfy_
    homodimer
    complexed with so4

Details for d1hcfa_

PDB Entry: 1hcf (more details), 2.7 Å

PDB Description: crystal structure of trkb-d5 bound to neurotrophin-4/5
PDB Compounds: (A:) neurotrophin-4

SCOPe Domain Sequences for d1hcfa_:

Sequence, based on SEQRES records: (download)

>d1hcfa_ g.17.1.3 (A:) Neurotrophin 4, NT4 {Human (Homo sapiens) [TaxId: 9606]}
gvsetapasrrgelavcdavsgwvtdrrtavdlrgrevevlgevpaaggsplrqyffetr
ckadnaeeggpgaggggcrgvdrrhwvseckakqsyvraltadaqgrvgwrwiridtacv
ctllsrt

Sequence, based on observed residues (ATOM records): (download)

>d1hcfa_ g.17.1.3 (A:) Neurotrophin 4, NT4 {Human (Homo sapiens) [TaxId: 9606]}
gvsetapasrrgelavcdavsgwvtdrrtavdlrgrevevlgevpaaggsplrqyffetr
ckadpgaggggcrgvdrrhwvseckakqsyvraltadaqgrvgwrwiridtacvctllsr
t

SCOPe Domain Coordinates for d1hcfa_:

Click to download the PDB-style file with coordinates for d1hcfa_.
(The format of our PDB-style files is described here.)

Timeline for d1hcfa_: