SCOPe 2.07: Domain d1guya1: 1guy A:1-143

Lineage for d1guya1 (1guy A:1-143)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)

6. Protein Malate dehydrogenase [51849] (13 species)

7. Species Chloroflexus aurantiacus [TaxId:1108] [69415] (7 PDB entries)
   Uniprot P80040

8. Domain d1guya1: 1guy A:1-143 [65582]
   Other proteins in same PDB: d1guya2, d1guyc2
   complexed with cd, nad

Details for d1guya1

PDB Entry: 1guy, 2.2 Å

PDB Description: structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases

PDB Compounds: (A:) malate dehydrogenase

SCOPe Domain Sequences for d1guya1:

Sequence, based on SEQRES records:

>d1guya1 c.2.1.5 (A:1-143) Malate dehydrogenase {Chloroflexus aurantiacus [TaxId: 1108]}
mrkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvt
gtnnyadtansdvivvtsgaprkpgmsredlikvnaditracisqaaplspnaviimvnn
pldamtylaaevsgfpkervigq

Sequence, based on observed residues (ATOM records):

>d1guya1 c.2.1.5 (A:1-143) Malate dehydrogenase {Chloroflexus aurantiacus [TaxId: 1108]}
mrkkisiigagfvgsttahwlaakelgdivlldivegvpqgkaldlyeaspiegfdvrvt
gtnnyadtansdvivvtsgalikvnaditracisqaaplspnaviimvnnpldamtylaa
evsgfpkervigq

Timeline for d1guya1:

• d1guya1 first appeared in SCOP 1.59
  
• d1guya1 appears in SCOPe 2.06
  
• d1guya1 appears in the current release, SCOPe 2.08