SCOPe 2.05: Domain d1gm9.1: 1gm9 A:,B:

Lineage for d1gm9.1 (1gm9 A:,B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.2: Penicillin acylase, catalytic domain [56244] (3 proteins)

6. Protein Penicillin acylase [56245] (2 species)
   also contains 2 all-alpha and a beta-barrel domains
   will be divided into domains in future release

7. Species Escherichia coli [TaxId:562] [56246] (24 PDB entries)

8. Domain d1gm9.1: 1gm9 A:,B: [65304]
   complexed with ca, edo, sox

Details for d1gm9.1

PDB Entry: 1gm9, 1.8 Å

PDB Description: crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism

PDB Compounds: (A:) penicillin g acylase alpha subunit, (B:) penicillin g acylase beta subunit

SCOPe Domain Sequences for d1gm9.1:

Sequence; same for both SEQRES and ATOM records:

>g1gm9.1 d.153.1.2 (A:,B:) Penicillin acylase {Escherichia coli [TaxId: 562]}
ssseikivrdeygmphiyandtwhlfygygyvvaqdrlfqmemarrstqgtvaevlgkdf
vkfdkdirrnywpdairaqiaalspedmsilqgyadgmnawidkvntnpetllpkqfntf
gftpkrwepfdvamifvgtmanrfsdstseidnlalltalkdkygvsqgmavfnqlkwlv
npsapttiavqesnyplkfnqqnsqtaXsnmwvigkskaqdakaimvngpqfgwyapayt
ygiglhgagydvtgntpfaypglvfghngviswgstagfgddvdifaerlsaekpgyylh
ngkwvkmlsreetitvkngqaetftvwrtvhgnilqtdqttqtayaksrawdgkevasll
awthqmkaknwqewtqqaakqaltinwyyadvngnigyvhtgaypdrqsghdprlpvpgt
gkwdwkgllpfemnpkvynpqsgyianwnnspqkdypasdlfaflwggadrvteidrlle
qkprltadqawdvirqtsrqdlnlrlflptlqaatsgltqsdprrqlvetltrwdginll
nddgktwqqpgsailnvwltsmlkrtvvaavpmpfdkwysasgyettqdgptgslnisvg
akilyeavqgdkspipqavdlfagkpqqevvlaaledtwetlskrygnnvsnwktpamal
tfrannffgvpqaaaeetrhqaeyqnrgtendmivfspttsdrpvlawdvvapgqsgfia
pdgtvdkhyedqlkmyenfgrkslwltkqdveahkesqevlhvqr

Timeline for d1gm9.1:

• d1gm9.1 first appeared in SCOP 1.59
  
• d1gm9.1 appears in SCOPe 2.04
  
• d1gm9.1 appears in SCOPe 2.06
  
• d1gm9.1 appears in the current release, SCOPe 2.08