SCOPe 2.08: Domain d1gl9c3: 1gl9 C:499-1054

Lineage for d1gl9c3 (1gl9 C:499-1054)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.10: Prokaryotic type I DNA topoisomerase [56711] (1 superfamily)
   4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8

4. Superfamily e.10.1: Prokaryotic type I DNA topoisomerase [56712] (2 families)
   duplication: the protein chain passing through the domains 2-4 makes two structural repeats
   The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV

5. Family e.10.1.1: Prokaryotic type I DNA topoisomerase [56713] (4 proteins)
   domain 4 contains the catalytic tyrosine residue

6. Protein Topoisomerase 'domain' of reverse gyrase [69890] (1 species)

7. Species Archaeoglobus fulgidus [TaxId:2234] [69891] (2 PDB entries)

8. Domain d1gl9c3: 1gl9 C:499-1054 [65296]
   Other proteins in same PDB: d1gl9b1, d1gl9b2, d1gl9c1, d1gl9c2
   protein/DNA complex; complexed with anp, mg

Details for d1gl9c3

PDB Entry: 1gl9, 3.2 Å

PDB Description: archaeoglobus fulgidus reverse gyrase complexed with adpnp

PDB Compounds: (C:) reverse gyrase

SCOPe Domain Sequences for d1gl9c3:

Sequence, based on SEQRES records:

>d1gl9c3 e.10.1.1 (C:499-1054) Topoisomerase 'domain' of reverse gyrase {Archaeoglobus fulgidus [TaxId: 2234]}
qefdlikpalfivesptkarqisrffgkpsvkvldgavvyeipmqkyvlmvtasighvvd
litnrgfhgvlvngrfvpvyasikrcrdcgyqftedrescpkcgsenvdnsrsriealrk
lahdaefvivgtdpdtegekiawdlknllsgcgavkraefhevtrrailealeslrdvde
nlvkaqvvrriedrwigfvlsqklwerfnnrnlsagraqtlvlgwiidrfqesrerrkia
ivrdfdlvlehdeeefdltiklveereelrtplppyttetmlsdanrilkfsvkqtmqia
qelfenglityhrtdstrvsdvgqriakeylgddfvgrewgesgahecirptrpltrddv
qrliqegvlvveglrwehfalydlifrrfmasqcrpfkvvvkkysiefdgktaeeerivr
aegrayelyravwvknelptgtfrvkaevksvpkvlpftqseiiqmmkergigrpstyat
ivdrlfmrnyvvekygrmiptklgidvfrflvrryakfvsedrtrdlesrmdaiergeld
ylkaledmyaeiksid

Sequence, based on observed residues (ATOM records):

>d1gl9c3 e.10.1.1 (C:499-1054) Topoisomerase 'domain' of reverse gyrase {Archaeoglobus fulgidus [TaxId: 2234]}
qefdlikpalfivesptkarqisrffgkpsvkvldgavvyeipmqkyvlmvtasighvvd
litnrgfhgvlvngrfvpvyasikrcrvdnsrsriealrklahdaefvivgtdpdtegek
iawdlknllsgcgavkraefhevtrrailealeslrdvdenlvkaqvvrriedrwigfvl
sqklwerfnnrnlsagraqtlvlgwiidrfqesrerrkiaivrdfdlvldeeefdltikl
veereelrtplppyttetmlsdanrilkfsvkqtmqiaqelfenglityhrtdstrvsdv
gqriakeylgddfvgrewgesgahecirptrpltrddvqrliqegvlvveglrwehfaly
dlifrrfmasqcrpfkvvvkkysiefdeeerivraegrayelyravwvknelptgtfrvk
aevksvpkvlpftqseiiqmmkergigrpstyativdrlfmrnyvvekygrmiptklgid
vfrflvrryakfvsedrtrdlesrmdaiergeldylkaledmyaeiksid

Timeline for d1gl9c3:

• d1gl9c3 first appeared in SCOP 1.59
  
• d1gl9c3 appears in SCOPe 2.07