Lineage for d1gija_ (1gij A:)

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 262793Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 262794Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 262795Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)
  6. 262839Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)
  7. 262840Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)
  8. 262870Domain d1gija_: 1gij A: [65219]
    complexed with 2pu; mutant

Details for d1gija_

PDB Entry: 1gij (more details), 2.2 Å

PDB Description: human cyclin dependent kinase 2 complexed with the cdk4 inhibitor

SCOP Domain Sequences for d1gija_:

Sequence, based on SEQRES records: (download)

>d1gija_ d.144.1.1 (A:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfehvhqdlktfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d1gija_ d.144.1.1 (A:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkiraireisllkelnhpnivklldvih
tenklylvfehvhqdlktfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpq
nllintegaikladfglavtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl

SCOP Domain Coordinates for d1gija_:

Click to download the PDB-style file with coordinates for d1gija_.
(The format of our PDB-style files is described here.)

Timeline for d1gija_: