SCOP 1.73: Domain d1eb1.1: 1eb1 L:,H:

Lineage for d1eb1.1 (1eb1 L:,H:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (163 PDB entries)

8. Domain d1eb1.1: 1eb1 L:,H: [64892]
   complexed with alc, mmo, pro

Details for d1eb1.1

PDB Entry: 1eb1, 1.8 Å

PDB Description: complex structure of human thrombin with n-methyl-arginine inhibitor

PDB Compounds: (H:) Thrombin heavy chain, (L:) Thrombin light chain

SCOP Domain Sequences for d1eb1.1:

Sequence; same for both SEQRES and ATOM records:

>g1eb1.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
cdaglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanv
gkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmk
spfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Timeline for d1eb1.1:

• d1eb1.1 first appeared in SCOP 1.59
  
• d1eb1.1 appears in SCOP 1.71
  
• d1eb1.1 appears in SCOP 1.75
  
• d1eb1.1 appears in the current release, SCOPe 2.08