SCOP 1.73: Domain d1ea2a_: 1ea2 A:

Lineage for d1ea2a_ (1ea2 A:)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.17: Cystatin-like [54402] (7 superfamilies)
   Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet

4. Superfamily d.17.4: NTF2-like [54427] (13 families)
   has a beta-alpha(2)-beta insertion after the main helix

5. Family d.17.4.3: Ketosteroid isomerase-like [54434] (2 proteins)

6. Protein Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI [54435] (2 species)

7. Species Pseudomonas putida [TaxId:303] [54437] (20 PDB entries)

8. Domain d1ea2a_: 1ea2 A: [64860]

Details for d1ea2a_

PDB Entry: 1ea2, 1.8 Å

PDB Description: Pseudoreversion of the Catalytic Activity of Y14F by the Additional Tyrosine-to-Phenylalanine Substitution(s) in the Hydrogen Bond Network of Delta-5-3-Ketosteroid Isomerase from Pheudomonas putida Biotype B

PDB Compounds: (A:) delta-5-3-ketosteroid isomerase.

SCOP Domain Sequences for d1ea2a_:

Sequence, based on SEQRES records:

>d1ea2a_ d.17.4.3 (A:) Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI {Pseudomonas putida [TaxId: 303]}
nlptaqevqglmarfielvdvgdieaivqmyaddatvedpfgqppihgreqiaafyrqgl
gggkvracltgpvrashngcgampfrvemvwngqpcaldvidvmrfdehgriqtmqayws
evnlsv

Sequence, based on observed residues (ATOM records):

>d1ea2a_ d.17.4.3 (A:) Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI {Pseudomonas putida [TaxId: 303]}
nlptaqevqglmarfielvdvgdieaivqmyaddatvedpfgqppihgreqiaafyrqgl
kvracltgpvrashngcgampfrvemvwngqpcaldvidvmrfdehgriqtmqaywsevn
lsv

Timeline for d1ea2a_:

• d1ea2a_ first appeared in SCOP 1.59
  
• d1ea2a_ appears in SCOP 1.71
  
• d1ea2a_ appears in SCOP 1.75
  
• d1ea2a_ appears in the current release, SCOPe 2.08