Lineage for d1e92a_ (1e92 A:)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 685975Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 685976Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 686289Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 686542Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 686545Species Leishmania major [TaxId:5664] [63926] (8 PDB entries)
  8. 686548Domain d1e92a_: 1e92 A: [64798]

Details for d1e92a_

PDB Entry: 1e92 (more details), 2.2 Å

PDB Description: pteridine reductase 1 from leishmania major complexed with nadp+ and dihydrobiopterin
PDB Compounds: (A:) pteridine reductase 1

SCOP Domain Sequences for d1e92a_:

Sequence, based on SEQRES records: (download)

>d1e92a_ c.2.1.2 (A:) Dihydropteridin reductase (pteridine reductase) {Leishmania major [TaxId: 5664]}
vpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqad
lsnvatapvsgadgsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrndedg
hepcvgdreametatadlfgsnaiapyflikafahrvagtpakhrgtnysiinmvdamtn
qpllgytiytmakgalegltrsaalelaplqirvngvgpglsvlvddmppavweghrskv
plyqrdssaaevsdvviflcsskakyitgtcvkvdggysltra

Sequence, based on observed residues (ATOM records): (download)

>d1e92a_ c.2.1.2 (A:) Dihydropteridin reductase (pteridine reductase) {Leishmania major [TaxId: 5664]}
vpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqad
lsnvatapapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrndgdreametat
adlfgsnaiapyflikafahrvagtpakhrgtnysiinmvdamtnqpllgytiytmakga
legltrsaalelaplqirvngvgpglsvlvddmppavweghrskvplyqrdssaaevsdv
viflcsskakyitgtcvkvdggysltra

SCOP Domain Coordinates for d1e92a_:

Click to download the PDB-style file with coordinates for d1e92a_.
(The format of our PDB-style files is described here.)

Timeline for d1e92a_: