Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021262Protein Bcl-2 [64524] (1 species)
  7. 3021263Species Human (Homo sapiens) [TaxId:9606] [64525] (18 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1g5m:
    • 3021287Domain d1g5ma_: 1g5m A: [60286]
      isoform 1
      has additional insertions and/or extensions that are not grouped together
  2. Domain(s) for 1gjh:
    • 3021286Domain d1gjha_: 1gjh A: [60575]
      isoform 2
      has additional insertions and/or extensions that are not grouped together
  3. Domain(s) for 1ysw:
    • 3021289Domain d1yswa2: 1ysw A:1-203 [123984]
      Other proteins in same PDB: d1yswa3
      automated match to d2o22a1
      complexed with 43b

      has additional insertions and/or extensions that are not grouped together
  4. Domain(s) for 2o21:
    • 3021288Domain d2o21a_: 2o21 A: [138882]
      automated match to d1gjha_
      complexed with 43b

      has additional insertions and/or extensions that are not grouped together
  5. Domain(s) for 2o22:
    • 3021285Domain d2o22a_: 2o22 A: [138883]
      automated match to d2o22a1
      complexed with liu

      has additional insertions and/or extensions that are not grouped together
  6. Domain(s) for 2o2f:
  7. Domain(s) for 4lvt:
    1. 3021276Domain d4lvta_: 4lvt A: [224767]
      automated match to d4aq3b_
      complexed with 1xj
    2. 3021277Domain d4lvtb_: 4lvt B: [224768]
      automated match to d4aq3b_
      complexed with 1xj
  8. Domain(s) for 4lxd:
  9. Domain(s) for 4lxe:
    1. 3021272Domain d4lxea_: 4lxe A: [307710]
      automated match to d1gjha_
      complexed with 1y1
    2. 3021273Domain d4lxeb_: 4lxe B: [307711]
      automated match to d1gjha_
      complexed with 1y1
  10. Domain(s) for 4man:
    1. 3021278Domain d4mana_: 4man A: [236460]
      automated match to d1gjha_
      complexed with 1y1
    2. 3021279Domain d4manb_: 4man B: [236461]
      automated match to d1gjha_
      complexed with 1y1
  11. Domain(s) for 5agw:
    1. 3021282Domain d5agwa_: 5agw A: [276647]
      automated match to d1gjha_
    2. 3021283Domain d5agwb_: 5agw B: [276646]
      automated match to d1gjha_
  12. Domain(s) for 6gl8:
  13. Domain(s) for 6o0k:
  14. Domain(s) for 6o0l:
    1. 3021280Domain d6o0la_: 6o0l A: [369167]
      automated match to d2o22a_
      complexed with cl, lbm, peg; mutant
    2. 3021281Domain d6o0lc_: 6o0l C: [369173]
      automated match to d2o22a_
      complexed with cl, lbm, peg; mutant
  15. Domain(s) for 6o0m:
  16. Domain(s) for 6o0o:
    1. 3021274Domain d6o0oa_: 6o0o A: [369164]
      automated match to d2o22a_
      complexed with f3q; mutant
    2. 3021275Domain d6o0oc_: 6o0o C: [369169]
      automated match to d2o22a_
      complexed with f3q; mutant
  17. Domain(s) for 6o0p:
  18. Domain(s) for 7lhb:
    1. 3021267Domain d7lhba_: 7lhb A: [403496]
      automated match to d2o22a_
      complexed with xzd
    2. 3021268Domain d7lhbb_: 7lhb B: [403498]
      automated match to d2o22a_
      complexed with xzd
    3. 3021269Domain d7lhbc_: 7lhb C: [403517]
      automated match to d2o22a_
      complexed with xzd

More info for Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Bcl-2

Timeline for Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Bcl-2: