SCOPe 2.08: Protein: Cell cycle checkpoint kinase chk1

Lineage for Protein: Cell cycle checkpoint kinase chk1

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
CaMK group; CAMKL subfamily; serine/threonine kinase

Species:

Human (Homo sapiens) [TaxId:9606] [64405] (100 PDB entries)
1. Domain for 1ia8:
  - Domain d1ia8a_: 1ia8 A: [62112]
    complexed with so4
2. Domain for 1nvq:
  - Domain d1nvqa_: 1nvq A: [86267]
    complex with peptide, chain B
    complexed with so4, ucn
3. Domain for 1nvr:
  - Domain d1nvra_: 1nvr A: [86268]
    complex with peptide, chain B
    complexed with so4, stu
4. Domain for 1nvs:
  - Domain d1nvsa_: 1nvs A: [86269]
    complex with peptide, chain B
    complexed with so4, ucm
5. Domain for 1zlt:
  - Domain d1zlta_: 1zlt A: [125257]
    automated match to d1ia8a_
    complexed with hym, so4
6. Domain for 1zys:
  - Domain d1zysa_: 1zys A: [162628]
    automated match to d1ia8a_
    complexed with 199, so4
7. Domain for 2ayp:
  - Domain d2aypa_: 2ayp A: [127568]
    automated match to d1ia8a_
    complexed with 43a
8. Domain for 2fga:
  - Domain d2fgaa_: 2fga A: [303825]
    automated match to d2gdoa_
9. Domain for 2ghg:
  - Domain d2ghga1: 2ghg A:2-270 [135177]
    automatically matched to d1ia8a_
    complexed with a53
10. Domain for 2hog:
  - Domain d2hoga_: 2hog A: [136642]
    automated match to d1ua2a_
    complexed with 710
11. Domain for 2qhm:
  - Domain d2qhma_: 2qhm A: [150788]
    automated match to d3tkha_
    complexed with 7cs
12. Domain for 2qhn:
  - Domain d2qhna_: 2qhn A: [150789]
    automated match to d3tkha_
    complexed with 582
13. Domain for 2r0u:
  - Domain d2r0ua_: 2r0u A: [151508]
    automated match to d3tkha_
    protein/DNA complex; complexed with m54
14. Domain for 2x8e:
  - Domain d2x8ea_: 2x8e A: [169945]
    automated match to d1ia8a_
    complexed with so4, x8e
15. Domains for 2ydj:
  1. Domain d2ydja_: 2ydj A: [170763]
    automated match to d1ia8a_
    complexed with po4, ydj
  2. Domain d2ydjb_: 2ydj B: [170764]
    automated match to d1ia8a_
    complexed with po4, ydj
16. Domain for 2ywp:
  - Domain d2ywpa_: 2ywp A: [140095]
    automated match to d1ia8a_
    complexed with a42
17. Domain for 3f9n:
  - Domain d3f9na_: 3f9n A: [209835]
    automated match to d1ua2a_
    protein/DNA complex; complexed with 38m, so4
18. Domain for 3jvr:
  - Domain d3jvra_: 3jvr A: [178846]
    automated match to d1ia8a_
    complexed with agx
19. Domain for 3jvs:
  - Domain d3jvsa_: 3jvs A: [178847]
    automated match to d1ia8a_
    complexed with agy
20. Domain for 3ot3:
  - Domain d3ot3a_: 3ot3 A: [183278]
    automated match to d1ia8a_
    complexed with 22k
21. Domain for 3ot8:
  - Domain d3ot8a_: 3ot8 A: [183279]
    automated match to d1ia8a_
    complexed with gol, mi5
22. Domain for 3pa3:
  - Domain d3pa3a_: 3pa3 A: [183610]
    automated match to d1ia8a_
    complexed with c70
23. Domain for 3pa4:
  - Domain d3pa4a_: 3pa4 A: [183611]
    automated match to d1ia8a_
    complexed with c72, gol
24. Domain for 3pa5:
  - Domain d3pa5a_: 3pa5 A: [183612]
    automated match to d1ia8a_
    complexed with c73, gol
25. Domain for 3tkh:
  - Domain d3tkha_: 3tkh A: [233691]
    automated match to d1tkia_
    complexed with 07s, so4
26. Domain for 3tki:
  - Domain d3tkia_: 3tki A: [233692]
    automated match to d1tkia_
    complexed with s25, so4
27. Domain for 3u9n:
  - Domain d3u9na_: 3u9n A: [186192]
    automated match to d1ia8a_
    complexed with 09h
28. Domain for 4fsm:
  - Domain d4fsma_: 4fsm A: [197166]
    automated match to d2x8da_
    complexed with gol, hk1, ipa, so4
29. Domain for 4fsn:
  - Domain d4fsna_: 4fsn A: [194785]
    automated match to d2x8da_
    complexed with a58, ipa, so4
30. Domain for 4fsq:
  - Domain d4fsqa_: 4fsq A: [221497]
    automated match to d4ftca_
    complexed with hk3, so4
31. Domain for 4fsr:
  - Domain d4fsra_: 4fsr A: [221498]
    automated match to d4ftca_
    complexed with hkc, so4
32. Domain for 4fst:
  - Domain d4fsta_: 4fst A: [192442]
    automated match to d2ghga1
    complexed with gol, hk4, ipa, so4
33. Domain for 4fsu:
  - Domain d4fsua_: 4fsu A: [194786]
    automated match to d2x8da_
    complexed with gol, hk5, ipa, so4
34. Domain for 4fsw:
  - Domain d4fswa_: 4fsw A: [221504]
    automated match to d4ftca_
    complexed with hk6, ipa, so4
35. Domain for 4fsy:
  - Domain d4fsya_: 4fsy A: [221505]
    automated match to d4ftca_
    complexed with gol, hk7, ipa, so4
36. Domain for 4fsz:
  - Domain d4fsza_: 4fsz A: [221506]
    automated match to d4ftca_
    complexed with hk8, ipa, so4
37. Domain for 4ft0:
  - Domain d4ft0a_: 4ft0 A: [221507]
    automated match to d4ftca_
    complexed with hk9, ipa, so4
38. Domain for 4ft3:
  - Domain d4ft3a_: 4ft3 A: [221508]
    automated match to d4ftca_
    complexed with gol, h1k, ipa, so4
39. Domain for 4ft5:
  - Domain d4ft5a_: 4ft5 A: [221509]
    automated match to d4ftca_
    complexed with gol, h2k, so4
40. Domain for 4ft7:
  - Domain d4ft7a_: 4ft7 A: [221510]
    automated match to d4ftca_
    complexed with gol, h3k, ipa, so4
41. Domain for 4ft9:
  - Domain d4ft9a_: 4ft9 A: [221511]
    automated match to d4ftca_
    complexed with h4k, so4
42. Domain for 4fta:
  - Domain d4ftaa_: 4fta A: [197170]
    automated match to d2x8da_
    complexed with gol, h5k, ipa, so4
43. Domain for 4ftc:
  - Domain d4ftca_: 4ftc A: [193571]
    automated match to d2x8da_
    complexed with gol, h6k, ipa, so4
44. Domain for 4fti:
  - Domain d4ftia_: 4fti A: [221512]
    automated match to d4ftca_
    complexed with gol, h7k, ipa, so4
45. Domain for 4ftj:
  - Domain d4ftja_: 4ftj A: [221513]
    automated match to d4ftca_
    complexed with h8k, ipa, so4
46. Domain for 4ftk:
  - Domain d4ftka_: 4ftk A: [221514]
    automated match to d4ftca_
    complexed with h9k, ipa, so4
47. Domain for 4ftl:
  - Domain d4ftla_: 4ftl A: [221515]
    automated match to d4ftca_
    complexed with h0k, ipa, so4
48. Domain for 4ftm:
  - Domain d4ftma_: 4ftm A: [221516]
    automated match to d4ftca_
    complexed with 1hk, gol, ipa, so4
49. Domain for 4ftn:
  - Domain d4ftna_: 4ftn A: [197162]
    automated match to d2x8da_
    complexed with 2hk, gol, ipa, so4
50. Domain for 4fto:
  - Domain d4ftoa_: 4fto A: [197167]
    automated match to d2x8da_
    complexed with 3hk, gol, ipa, so4
51. Domain for 4ftq:
  - Domain d4ftqa_: 4ftq A: [197168]
    automated match to d2x8da_
    complexed with 4hk, gol, ipa, so4
52. Domain for 4ftr:
  - Domain d4ftra_: 4ftr A: [197161]
    automated match to d2x8da_
    complexed with 5hk, gol, ipa, so4
53. Domain for 4ftt:
  - Domain d4ftta_: 4ftt A: [221517]
    automated match to d4ftca_
    complexed with 6hk, ipa, so4
54. Domain for 4ftu:
  - Domain d4ftua_: 4ftu A: [221518]
    automated match to d4ftca_
    complexed with 7hk, gol, ipa, so4
55. Domain for 4gh2:
  - Domain d4gh2a_: 4gh2 A: [197177]
    automated match to d2x8da_
    complexed with gol, hk0, ipa, so4
56. Domain for 4hyh:
  - Domain d4hyha_: 4hyh A: [196964]
    automated match to d2x8da_
    complexed with 1am
57. Domain for 4hyi:
  - Domain d4hyia_: 4hyi A: [222794]
    automated match to d1ia8a_
    complexed with 1ao, gol
58. Domain for 4jik:
  - Domain d4jika_: 4jik A: [196866]
    automated match to d2x8da_
    complexed with 1ko
59. Domain for 4qye:
  - Domain d4qyea_: 4qye A: [261946]
    automated match to d2ydia_
    complexed with 3dl
60. Domain for 4qyf:
  - Domain d4qyfa_: 4qyf A: [267370]
    automated match to d2ydia_
    complexed with 3dv
61. Domains for 4qyg:
  1. Domain d4qyga_: 4qyg A: [267371]
    automated match to d2ydia_
    complexed with 3dw
  2. Domain d4qygb_: 4qyg B: [267372]
    automated match to d2ydia_
    complexed with 3dw
62. Domains for 4qyh:
  1. Domain d4qyha_: 4qyh A: [261945]
    automated match to d2ydia_
    complexed with 3dx
  2. Domain d4qyhb_: 4qyh B: [261944]
    automated match to d2ydia_
    complexed with 3dx
63. Domain for 4rvk:
  - Domain d4rvka_: 4rvk A: [273455]
    automated match to d2ydia_
    complexed with 3xk
64. Domain for 4rvl:
  - Domain d4rvla_: 4rvl A: [273450]
    automated match to d2ydia_
    complexed with 3xl
65. Domain for 4rvm:
  - Domain d4rvma_: 4rvm A: [273453]
    automated match to d2ydia_
    complexed with 3x7
66. Domain for 5dls:
  - Domain d5dlsa_: 5dls A: [278129]
    automated match to d2ydia_
    complexed with 5cv, so4
67. Domain for 5oop:
  - Domain d5oopa_: 5oop A: [340594]
    automated match to d2ydia_
    complexed with anp; mutant
68. Domain for 5oor:
  - Domain d5oora_: 5oor A: [340581]
    automated match to d2ydia_
    complexed with cl, stu; mutant
69. Domain for 5oot:
  - Domain d5oota_: 5oot A: [340598]
    automated match to d2ydia_
    complexed with 4k4; mutant
70. Domain for 5op2:
  - Domain d5op2a_: 5op2 A: [340629]
    automated match to d2ydia_
    complexed with a0q, cl; mutant
71. Domain for 5op4:
  - Domain d5op4a_: 5op4 A: [340583]
    automated match to d2ydia_
    complexed with a0t; mutant
72. Domain for 5op5:
  - Domain d5op5a_: 5op5 A: [340676]
    automated match to d2ydia_
    complexed with 3fe, cl; mutant
73. Domain for 5op7:
  - Domain d5op7a_: 5op7 A: [340560]
    automated match to d2ydia_
    complexed with a1k, cl, na; mutant
74. Domain for 5opb:
  - Domain d5opba_: 5opb A: [340547]
    automated match to d2ydia_
    complexed with a1n, cl; mutant
75. Domain for 5opr:
  - Domain d5opra_: 5opr A: [340565]
    automated match to d2ydia_
    complexed with a3e; mutant
76. Domain for 5ops:
  - Domain d5opsa_: 5ops A: [340578]
    automated match to d2ydia_
    complexed with a3q; mutant
77. Domain for 5opu:
  - Domain d5opua_: 5opu A: [340558]
    automated match to d2ydia_
    complexed with a3k, cl; mutant
78. Domain for 5opv:
  - Domain d5opva_: 5opv A: [340584]
    automated match to d2ydia_
    complexed with a3h; mutant
79. Domain for 5oq5:
  - Domain d5oq5a_: 5oq5 A: [340571]
    automated match to d2ydia_
    complexed with 4k4, mes; mutant
80. Domain for 5oq6:
  - Domain d5oq6a_: 5oq6 A: [340622]
    automated match to d2ydia_
    complexed with 4k4, cl; mutant
81. Domains for 5oq7:
  1. Domain d5oq7a_: 5oq7 A: [340586]
    automated match to d2ydia_
    complexed with a0q; mutant
  2. Domain d5oq7b_: 5oq7 B: [340604]
    automated match to d2ydia_
    complexed with a0q; mutant
82. Domain for 5oq8:
  - Domain d5oq8a_: 5oq8 A: [340628]
    automated match to d2ydia_
    complexed with a0q; mutant
83. Domain for 6fc8:
  - Domain d6fc8a_: 6fc8 A: [350557]
    automated match to d3tkia_
    complexed with d4q, so4
84. Domain for 6fcf:
  - Domain d6fcfa_: 6fcf A: [350597]
    automated match to d3tkia_
    complexed with d58, so4
85. Domain for 6fck:
  - Domain d6fcka_: 6fck A: [350651]
    automated match to d3tkia_
    complexed with d4z, so4
86. Domains for 7akm:
  1. Domain d7akma_: 7akm A: [402975]
    automated match to d5oora_
    complexed with ags, cit, edo, mg
  2. Domain d7akmb_: 7akm B: [402961]
    automated match to d5oora_
    complexed with ags, cit, edo, mg
87. Domain for 7bjd:
  - Domain d7bjda_: 7bjd A: [417661]
    automated match to d5oora_
    complexed with cl, tvt; mutant
88. Domain for 7bje:
  - Domain d7bjea_: 7bje A: [417662]
    automated match to d5oora_
    complexed with ade, cl; mutant
89. Domain for 7bjh:
  - Domain d7bjha_: 7bjh A: [417663]
    automated match to d5oora_
    complexed with 42c, cl; mutant
90. Domain for 7bjj:
  - Domain d7bjja_: 7bjj A: [417664]
    automated match to d5oora_
    complexed with cl, tvw; mutant
91. Domain for 7bjm:
  - Domain d7bjma_: 7bjm A: [417665]
    automated match to d5oora_
    complexed with tw2; mutant
92. Domain for 7bjo:
  - Domain d7bjoa_: 7bjo A: [417666]
    automated match to d5oora_
    complexed with twk; mutant
93. Domain for 7bjr:
  - Domain d7bjra_: 7bjr A: [417667]
    automated match to d5oora_
    complexed with twh; mutant
94. Domains for 7bjx:
  1. Domain d7bjxa_: 7bjx A: [417668]
    automated match to d5oora_
    complexed with u0q; mutant
  2. Domain d7bjxb_: 7bjx B: [417669]
    automated match to d5oora_
    complexed with u0q; mutant
95. Domain for 7bk1:
  - Domain d7bk1a_: 7bk1 A: [417670]
    automated match to d5oora_
    complexed with cl, u0n; mutant
96. Domain for 7bk2:
  - Domain d7bk2a_: 7bk2 A: [417671]
    automated match to d5oora_
    complexed with cl, u0k; mutant
97. Domain for 7bk3:
  - Domain d7bk3a_: 7bk3 A: [417672]
    automated match to d5oora_
    complexed with cl, u0t; mutant
98. Domain for 7bkn:
  - Domain d7bkna_: 7bkn A: [417673]
    automated match to d2ydia_
    complexed with ade, so4
99. Domain for 7bko:
  - Domain d7bkoa_: 7bko A: [417674]
    automated match to d2ydia_
    complexed with tvw
100. Domain for 7mck:
  - Domain d7mcka_: 7mck A: [405648]
    automated match to d5oora_
    complexed with yxd; mutant

More info for Protein Cell cycle checkpoint kinase chk1 from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein Cell cycle checkpoint kinase chk1 from d.144.1.7: Protein kinases, catalytic subunit:

Protein Cell cycle checkpoint kinase chk1 from d.144.1.7: Protein kinases, catalytic subunit first appeared in SCOP 1.57, called Protein Cell cycle checkpoint kinase chk1 from d.144.1.1: Serine/threonin kinases
Protein Cell cycle checkpoint kinase chk1 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOPe 2.07