SCOPe 2.08: Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

Lineage for Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.97: Cytidine deaminase-like [53926] (2 superfamilies)
   core: alpha-beta(2)-(alpha-beta)2; 3 layers (a/b/a); mixed beta-sheet of 4 strands, order 2134; strand 1 is antiparallel to the rest

4. Superfamily c.97.1: Cytidine deaminase-like [53927] (7 families)
   contains extra C-terminal strand 5, order 21345

5. Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64198] (2 proteins)
   duplication: consists of two domains of this fold with extra secondary structures within and in between the two core motifs

Proteins:

1. AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC [64199] (3 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [64200] (9 PDB entries)
      Uniprot P31335

   2. Species Human (Homo sapiens) [TaxId:9606] [102716] (3 PDB entries)

   3. Species Thermotoga maritima [TaxId:2336] [142844] (1 PDB entry)
      Uniprot Q9X0X6 158-452

2. automated matches [347771] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [347772] (2 PDB entries)

More info for Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

Timeline for Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC:

• Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC first appeared in SCOP 1.57, called Family c.97.2.1: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
  
• Family c.97.1.4: AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC appears in SCOPe 2.07