Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2143226Fold c.92: Chelatase-like [53799] (3 superfamilies)
    duplication: tandem repeat of two domains; 3 layers (a/b/a); parallel beta-sheet of 4 strands, order 2134
  4. 2143227Superfamily c.92.1: Chelatase [53800] (4 families) (S)
    interdomain linker is short; swapping of C-terminal helices between the two domains
  5. 2143228Family c.92.1.1: Ferrochelatase [53801] (2 protein domains)
    automatically mapped to Pfam PF00762
  6. 2143229Protein Ferrochelatase [53802] (3 species)
  7. 2143251Species Human (Homo sapiens) [TaxId:9606] [64189] (21 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1hrk:
    1. 2143262Domain d1hrka_: 1hrk A: [61228]
      complexed with chd, fes
    2. 2143263Domain d1hrkb_: 1hrk B: [61229]
      complexed with chd, fes
  2. Domain(s) for 2hrc:
    1. 2143258Domain d2hrca_: 2hrc A: [136687]
      automated match to d1hrka_
      complexed with chd, cl, fes, gol, imd
    2. 2143259Domain d2hrcb_: 2hrc B: [136688]
      automated match to d1hrka_
      complexed with chd, cl, fes, gol, imd
  3. Domain(s) for 2hre:
    1. 2143286Domain d2hrea_: 2hre A: [165220]
      automated match to d1hrka_
      complexed with chd, fes, pp9
    2. 2143287Domain d2hreb_: 2hre B: [165221]
      automated match to d1hrka_
      complexed with chd, fes, pp9
    3. 2143288Domain d2hrec_: 2hre C: [165222]
      automated match to d1hrka_
      complexed with chd, fes, pp9
    4. 2143289Domain d2hred_: 2hre D: [165223]
      automated match to d1hrka_
      complexed with chd, fes, pp9
  4. Domain(s) for 2pnj:
    1. 2143280Domain d2pnja_: 2pnj A: [167224]
      automated match to d1hrka_
      complexed with chd, fes; mutant
    2. 2143281Domain d2pnjb_: 2pnj B: [167225]
      automated match to d1hrka_
      complexed with chd, fes; mutant
  5. Domain(s) for 2po5:
    1. 2143268Domain d2po5a_: 2po5 A: [167230]
      automated match to d1hrka_
      complexed with chd, fes; mutant
    2. 2143269Domain d2po5b_: 2po5 B: [167231]
      automated match to d1hrka_
      complexed with chd, fes; mutant
  6. Domain(s) for 2po7:
    1. 2143270Domain d2po7a_: 2po7 A: [167232]
      automated match to d1hrka_
      complexed with chd, fes; mutant
    2. 2143271Domain d2po7b_: 2po7 B: [167233]
      automated match to d1hrka_
      complexed with chd, fes; mutant
  7. Domain(s) for 2qd1:
    1. 2143276Domain d2qd1a_: 2qd1 A: [167523]
      automated match to d1hrka_
      complexed with chd, fes, imd, pp9
    2. 2143277Domain d2qd1b_: 2qd1 B: [167524]
      automated match to d1hrka_
      complexed with chd, fes, imd, pp9
    3. 2143278Domain d2qd1c_: 2qd1 C: [167525]
      automated match to d1hrka_
      complexed with chd, fes, imd, pp9
    4. 2143279Domain d2qd1d_: 2qd1 D: [167526]
      automated match to d1hrka_
      complexed with chd, fes, imd, pp9
  8. Domain(s) for 2qd3:
    1. 2143266Domain d2qd3a_: 2qd3 A: [167529]
      automated match to d1hrka_
      complexed with chd, fes, gol, hem
    2. 2143267Domain d2qd3b_: 2qd3 B: [167530]
      automated match to d1hrka_
      complexed with chd, fes, gol, hem
  9. Domain(s) for 2qd4:
    1. 2143264Domain d2qd4a_: 2qd4 A: [167531]
      automated match to d1hrka_
      complexed with chd, cl, fes, gol
    2. 2143265Domain d2qd4b_: 2qd4 B: [167532]
      automated match to d1hrka_
      complexed with chd, cl, fes, gol
  10. Domain(s) for 2qd5:
    1. 2143282Domain d2qd5a_: 2qd5 A: [167533]
      automated match to d1hrka_
      complexed with acy, chd, fes, gol, oxy, pb, pp9
    2. 2143283Domain d2qd5b_: 2qd5 B: [167534]
      automated match to d1hrka_
      complexed with acy, chd, fes, gol, oxy, pb, pp9
  11. Domain(s) for 3aqi:
    1. 2143254Domain d3aqia_: 3aqi A: [172305]
      automated match to d1hrka_
      complexed with chd, fes, gol
    2. 2143255Domain d3aqib_: 3aqi B: [172306]
      automated match to d1hrka_
      complexed with chd, fes, gol
  12. Domain(s) for 3hcn:
    1. 2143252Domain d3hcna_: 3hcn A: [177386]
      automated match to d1hrka_
      complexed with bct, chd, fes, gol, hem, imd, so4
    2. 2143253Domain d3hcnb_: 3hcn B: [177387]
      automated match to d1hrka_
      complexed with bct, chd, fes, gol, hem, imd, so4
  13. Domain(s) for 3hcp:
    1. 2143260Domain d3hcpa_: 3hcp A: [177390]
      automated match to d1hrka_
      complexed with chd, fde, fes, gol, imd
    2. 2143261Domain d3hcpb_: 3hcp B: [177391]
      automated match to d1hrka_
      complexed with chd, fde, fes, gol, imd
  14. Domain(s) for 3hcr:
    1. 2143272Domain d3hcra_: 3hcr A: [177392]
      automated match to d1hrka_
      complexed with chd, cl, fde, fes, gol, imd, oxy, so4
    2. 2143273Domain d3hcrb_: 3hcr B: [177393]
      automated match to d1hrka_
      complexed with chd, cl, fde, fes, gol, imd, oxy, so4
  15. Domain(s) for 3w1w:
    1. 2143274Domain d3w1wa_: 3w1w A: [233903]
      automated match to d3w1wb_
      complexed with chd, edo, fes, sal
    2. 2143275Domain d3w1wb_: 3w1w B: [228280]
      automated match to d3aqia_
      complexed with chd, edo, fes, sal
  16. Domain(s) for 4f4d:
    1. 2143256Domain d4f4da_: 4f4d A: [194712]
      automated match to d2hrca_
      complexed with chd, cl, fes, gol
    2. 2143257Domain d4f4db_: 4f4d B: [194711]
      automated match to d2hrca_
      complexed with chd, cl, fes, gol
  17. Domain(s) for 4f4g:
    1. 2143290Domain d4f4ga_: 4f4g A: [196705]
      automated match to d2hrca_
      complexed with chd, cl, fes, gol
    2. 2143291Domain d4f4gb_: 4f4g B: [196704]
      automated match to d2hrca_
      complexed with chd, cl, fes, gol
  18. Domain(s) for 4kla:
    1. 2143294Domain d4klaa_: 4kla A: [256869]
      automated match to d3aqia_
      complexed with chd, fes, gol, pp9
    2. 2143295Domain d4klab_: 4kla B: [262832]
      automated match to d4klaa_
      complexed with chd, fes, gol, pp9
  19. Domain(s) for 4klc:
    1. 2143296Domain d4klca_: 4klc A: [256870]
      automated match to d3aqia_
      complexed with fes, gol, hem; mutant
    2. 2143297Domain d4klcb_: 4klc B: [262833]
      automated match to d4klaa_
      complexed with fes, gol, hem; mutant
  20. Domain(s) for 4klr:
    1. 2143284Domain d4klra_: 4klr A: [256872]
      automated match to d3aqia_
      complexed with bct, chd, cl, fes, gol, hem, imd
    2. 2143285Domain d4klrb_: 4klr B: [256871]
      automated match to d3aqia_
      complexed with bct, chd, cl, fes, gol, hem, imd
  21. Domain(s) for 4kmm:
    1. 2143292Domain d4kmma_: 4kmm A: [256873]
      automated match to d3aqia_
      complexed with chd, cl, fes, hem
    2. 2143293Domain d4kmmb_: 4kmm B: [262834]
      automated match to d4klaa_
      complexed with chd, cl, fes, hem

More info for Species Human (Homo sapiens) [TaxId:9606] from c.92.1.1 Ferrochelatase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.92.1.1 Ferrochelatase: