SCOPe 2.08: Protein: Manganese-dependent inorganic pyrophosphatase (family II)

Lineage for Protein: Manganese-dependent inorganic pyrophosphatase (family II)

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.107: DHH phosphoesterases [64181] (1 superfamily)
consists of two non-similar domains
Domain 1 has parallel sheet of 6 strands, order 321456
Domain 2 has mixed sheet of 5 strands, order 12345; strands 1 & 4 are antiparallel to the rest

Superfamily c.107.1: DHH phosphoesterases [64182] (3 families)
constituent families have similar domain organization with variable interdomain linker and spatial arrangement of the domains
Family c.107.1.1: Manganese-dependent inorganic pyrophosphatase (family II) [64183] (2 proteins)
Protein Manganese-dependent inorganic pyrophosphatase (family II) [64184] (3 species)

Species:

Bacillus subtilis [TaxId:1423] [69610] (5 PDB entries)
Uniprot P37487
1. Domains for 1k23:
  1. Domain d1k23a_: 1k23 A: [68029]
    complexed with mn
  2. Domain d1k23b_: 1k23 B: [68030]
    complexed with mn
  3. Domain d1k23c_: 1k23 C: [68031]
    complexed with mn
  4. Domain d1k23d_: 1k23 D: [68032]
    complexed with mn
    fragment; missing more than one-third of the common structure and/or sequence
2. Domains for 1wpm:
  1. Domain d1wpma_: 1wpm A: [114824]
    complexed with pg4, so4
  2. Domain d1wpmb_: 1wpm B: [114825]
    complexed with pg4, so4
3. Domains for 1wpn:
  1. Domain d1wpna_: 1wpn A: [114826]
    N-terminal core only
    complexed with mn, so4
    fragment; missing more than one-third of the common structure and/or sequence
  2. Domain d1wpnb_: 1wpn B: [114827]
    N-terminal core only
    complexed with mn, so4
    fragment; missing more than one-third of the common structure and/or sequence
4. Domains for 2haw:
  1. Domain d2hawa_: 2haw A: [136299]
    automated match to d1k23c_
    complexed with 1pe, 2pn, cl, f, gol, mg, pg4, so4
  2. Domain d2hawb_: 2haw B: [136300]
    automated match to d1k23c_
    complexed with 1pe, 2pn, cl, f, gol, mg, pg4, so4
5. Domains for 2iw4:
  1. Domain d2iw4a_: 2iw4 A: [165714]
    automated match to d1k23c_
    complexed with 2pn, fe, gol, mg, mn, pg4, so4; mutant
  2. Domain d2iw4b_: 2iw4 B: [165715]
    automated match to d1k23c_
    complexed with 2pn, fe, gol, mg, mn, pg4, so4; mutant
Streptococcus gordonii [TaxId:1302] [69609] (2 PDB entries)
Uniprot P95765
1. Domains for 1k20:
  1. Domain d1k20a_: 1k20 A: [68027]
    complexed with gol, mn, so4
  2. Domain d1k20b_: 1k20 B: [68028]
    complexed with gol, mn, so4
2. Domains for 1wpp:
  1. Domain d1wppa_: 1wpp A: [114828]
    complexed with cl, so4, zn
  2. Domain d1wppb_: 1wpp B: [114829]
    complexed with cl, so4, zn
Streptococcus mutans [TaxId:1309] [64185] (1 PDB entry)
- Domains for 1i74:
  1. Domain d1i74a_: 1i74 A: [61867]
    CASP4
    complexed with mg, mn, so4
  2. Domain d1i74b_: 1i74 B: [61868]
    CASP4
    complexed with mg, mn, so4

More info for Protein Manganese-dependent inorganic pyrophosphatase (family II) from c.107.1.1: Manganese-dependent inorganic pyrophosphatase (family II)

Timeline for Protein Manganese-dependent inorganic pyrophosphatase (family II) from c.107.1.1: Manganese-dependent inorganic pyrophosphatase (family II):

Protein Manganese-dependent inorganic pyrophosphatase (family II) from c.107.1.1: Manganese-dependent inorganic pyrophosphatase (family II) first appeared in SCOP 1.57, called Protein Manganese-dependent inorganic pyrophosphatase from c.107.1.1: Manganese-dependent inorganic pyrophosphatase
Protein Manganese-dependent inorganic pyrophosphatase (family II) from c.107.1.1: Manganese-dependent inorganic pyrophosphatase (family II) appears in SCOPe 2.07