SCOP 1.69: Species: Human (Homo sapiens)

Root: SCOP 1.69
Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (5 proteins)
silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
Protein Sirt2 histone deacetylase [63987] (1 species)
Species Human (Homo sapiens) [TaxId:9606] [63988] (1 PDB entry)

Domain(s) for 1j8f:
1. Domain d1j8fa_: 1j8f A: [62738]
2. Domain d1j8fb_: 1j8f B: [62739]
3. Domain d1j8fc_: 1j8f C: [62740]

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase:

Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase first appeared in SCOP 1.57
Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase appears in SCOP 1.67
Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase appears in SCOP 1.71
Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase appears in the current release, SCOPe 2.08