SCOPe 2.07: Protein: Breast cancer associated protein, BRCA1

Lineage for Protein: Breast cancer associated protein, BRCA1

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.15: BRCT domain [52112] (1 superfamily)
3 layers, a/b/a; core: parallel beta-sheet of 4 strands, order 2134
Superfamily c.15.1: BRCT domain [52113] (6 families)
Pfam PF00533
Family c.15.1.3: BRCT domain [63955] (1 protein)
Protein Breast cancer associated protein, BRCA1 [63956] (2 species)
duplication: tandem repeat of BRCT domain

Species:

Human (Homo sapiens) [TaxId:9606] [63957] (15 PDB entries)
Uniprot P38398 1649-1863
1. Domains for 1jnx:
  1. Domain d1jnxx1: 1jnx X:1649-1757 [63201]
    complexed with ni
  2. Domain d1jnxx2: 1jnx X:1758-1859 [63202]
    complexed with ni
2. Domains for 1n5o:
  1. Domain d1n5ox1: 1n5o X:1649-1757 [80033]
    complexed with co, so4; mutant
  2. Domain d1n5ox2: 1n5o X:1758-1859 [80034]
    complexed with co, so4; mutant
3. Domain for 1oqa:
  - Domain d1oqaa1: 1oqa A:2-110 [104021]
    Other proteins in same PDB: d1oqaa2
    C-terminal domain only
4. Domains for 1t15:
  1. Domain d1t15a1: 1t15 A:1649-1757 [99067]
  2. Domain d1t15a2: 1t15 A:1758-1859 [99068]
5. Domains for 1t29:
  1. Domain d1t29a1: 1t29 A:1649-1757 [99076]
  2. Domain d1t29a2: 1t29 A:1758-1859 [99077]
6. Domains for 1t2u:
  1. Domain d1t2ua1: 1t2u A:1649-1757 [99096]
    complexed with co, so4
  2. Domain d1t2ua2: 1t2u A:1758-1859 [99097]
    complexed with co, so4
7. Domains for 1t2v:
  1. Domain d1t2va1: 1t2v A:1649-1757 [99098]
  2. Domain d1t2va2: 1t2v A:1758-1859 [99099]
  3. Domain d1t2vb1: 1t2v B:1646-1757 [99100]
  4. Domain d1t2vb2: 1t2v B:1758-1859 [99101]
  5. Domain d1t2vc1: 1t2v C:1649-1757 [99102]
  6. Domain d1t2vc2: 1t2v C:1758-1859 [99103]
  7. Domain d1t2vd1: 1t2v D:1647-1757 [99104]
  8. Domain d1t2vd2: 1t2v D:1758-1856 [99105]
  9. Domain d1t2ve1: 1t2v E:1649-1757 [99106]
  10. Domain d1t2ve2: 1t2v E:1758-1859 [99107]
8. Domains for 1y98:
  1. Domain d1y98a1: 1y98 A:1650-1756 [122775]
    automatically matched to d1l0ba1
    complexed with co, so4
  2. Domain d1y98a2: 1y98 A:1760-1855 [122776]
    automatically matched to d1l0ba2
    complexed with co, so4
9. Domains for 2ing:
  1. Domain d2ingx1: 2ing X:1650-1756 [147739]
    automatically matched to d1l0ba1
    complexed with co, so4; mutant
  2. Domain d2ingx2: 2ing X:1760-1855 [147740]
    automatically matched to d1l0ba2
    complexed with co, so4; mutant
10. Domains for 3coj:
  1. Domain d3coja1: 3coj A:1650-1756 [156857]
    automatically matched to d1l0ba1
    protein/DNA complex
  2. Domain d3coja2: 3coj A:1760-1855 [156858]
    automatically matched to d1l0ba2
    protein/DNA complex
  3. Domain d3cojb1: 3coj B:1650-1756 [156859]
    automatically matched to d1l0ba1
    protein/DNA complex
  4. Domain d3cojb2: 3coj B:1760-1855 [156860]
    automatically matched to d1l0ba2
    protein/DNA complex
  5. Domain d3cojc1: 3coj C:1650-1756 [156861]
    automatically matched to d1l0ba1
    protein/DNA complex
  6. Domain d3cojc2: 3coj C:1760-1855 [156862]
    automatically matched to d1l0ba2
    protein/DNA complex
  7. Domain d3cojd1: 3coj D:1650-1756 [156863]
    automatically matched to d1l0ba1
    protein/DNA complex
  8. Domain d3cojd2: 3coj D:1760-1855 [156864]
    automatically matched to d1l0ba2
    protein/DNA complex
  9. Domain d3coje1: 3coj E:1650-1756 [156865]
    automatically matched to d1l0ba1
    protein/DNA complex
  10. Domain d3coje2: 3coj E:1760-1855 [156866]
    automatically matched to d1l0ba2
    protein/DNA complex
  11. Domain d3cojf1: 3coj F:1650-1756 [156867]
    automatically matched to d1l0ba1
    protein/DNA complex
  12. Domain d3cojf2: 3coj F:1760-1855 [156868]
    automatically matched to d1l0ba2
    protein/DNA complex
  13. Domain d3cojg1: 3coj G:1650-1756 [156869]
    automatically matched to d1l0ba1
    protein/DNA complex
  14. Domain d3cojg2: 3coj G:1760-1855 [156870]
    automatically matched to d1l0ba2
    protein/DNA complex
  15. Domain d3cojx1: 3coj X:1650-1756 [156871]
    automatically matched to d1l0ba1
    protein/DNA complex
  16. Domain d3cojx2: 3coj X:1760-1855 [156872]
    automatically matched to d1l0ba2
    protein/DNA complex
11. Domains for 3pxa:
  1. Domain d3pxaa1: 3pxa A:1649-1757 [214964]
    automated match to d1t15a1
    complexed with ni, so4
  2. Domain d3pxaa2: 3pxa A:1758-1859 [214965]
    automated match to d1t15a2
    complexed with ni, so4
12. Domains for 3pxb:
  1. Domain d3pxba1: 3pxb A:1649-1757 [214966]
    automated match to d1t15a1
    complexed with ni, so4
  2. Domain d3pxba2: 3pxb A:1758-1859 [214967]
    automated match to d1t15a2
    complexed with ni, so4
13. Domains for 3pxc:
  1. Domain d3pxcx1: 3pxc X:1649-1757 [214968]
    automated match to d1t15a1
    complexed with ni, so4
  2. Domain d3pxcx2: 3pxc X:1758-1859 [214969]
    automated match to d1t15a2
    complexed with ni, so4
14. Domains for 3pxd:
  1. Domain d3pxda1: 3pxd A:1649-1757 [214970]
    automated match to d1t15a1
    complexed with ni, so4
  2. Domain d3pxda2: 3pxd A:1758-1859 [214971]
    automated match to d1t15a2
    complexed with ni, so4
15. Domains for 4ofb:
  1. Domain d4ofba1: 4ofb A:1649-1757 [271396]
    automated match to d1t15a1
    protein/DNA complex
  2. Domain d4ofba2: 4ofb A:1758-1859 [271403]
    automated match to d1t15a2
    protein/DNA complex
Norway rat (Rattus norvegicus) [TaxId:10116] [75147] (1 PDB entry)
- Domains for 1l0b:
  1. Domain d1l0ba1: 1l0b A:1591-1702 [73391]
  2. Domain d1l0ba2: 1l0b A:1705-1801 [73392]

More info for Protein Breast cancer associated protein, BRCA1 from c.15.1.3: BRCT domain

Timeline for Protein Breast cancer associated protein, BRCA1 from c.15.1.3: BRCT domain:

Protein Breast cancer associated protein, BRCA1 from c.15.1.3: BRCT domain first appeared in SCOP 1.57, called Protein Breast cancer associated protein, BRCA1 from c.15.1.3: Breast cancer associated protein, BRCA1
Protein Breast cancer associated protein, BRCA1 from c.15.1.3: BRCT domain appears in SCOPe 2.06
Protein Breast cancer associated protein, BRCA1 from c.15.1.3: BRCT domain appears in the current release, SCOPe 2.08