Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 |
Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species) |
Human (Homo sapiens) [TaxId:9606] [102152] (3 PDB entries) |
Domain d1so8a_: 1so8 A: [98940] complexed with cl, na |
Domain d1u7ta_: 1u7t A: [113099] |
Domain d1u7tb_: 1u7t B: [113100] |
Domain d1u7tc_: 1u7t C: [113101] |
Domain d1u7td_: 1u7t D: [113102] complexed with nad, tdt; mutant |
Domain d2o23a1: 2o23 A:6-253 [138884] automatically matched to d1so8a_ complexed with gol, nad |
Domain d2o23b1: 2o23 B:6-253 [138885] automatically matched to d1so8a_ complexed with gol, nad |
Rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries) |
Domain d1e3sa_: 1e3s A: [59201] |
Domain d1e3sb_: 1e3s B: [59202] |
Domain d1e3sc_: 1e3s C: [59203] |
Domain d1e3sd_: 1e3s D: [59204] complexed with nad |
Domain d1e3wa_: 1e3w A: [59207] |
Domain d1e3wb_: 1e3w B: [59208] |
Domain d1e3wc_: 1e3w C: [59209] |
Domain d1e3wd_: 1e3w D: [59210] CASP4 complexed with aae, nad, so4, trs |
Domain d1e6wa_: 1e6w A: [59326] |
Domain d1e6wb_: 1e6w B: [59327] |
Domain d1e6wc_: 1e6w C: [59328] |
Domain d1e6wd_: 1e6w D: [59329] complexed with est, nad |
Thermus thermophilus [TaxId:274] [89525] (1 PDB entry) |
Domain d1uaya_: 1uay A: [88390] |
Domain d1uayb_: 1uay B: [88391] complexed with adn |
Timeline for Protein Type II 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases: