Lineage for Protein: 3-hydroxyacyl-CoA dehydrogenase

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 307887Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 307888Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families) (S)
  5. 308075Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (33 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 308113Protein 3-hydroxyacyl-CoA dehydrogenase [63933] (2 species)

Species:

  1. 308114Rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries)
    1. Domains for 1e3s:
      1. 308119Domain d1e3sa_: 1e3s A: [59201]
      2. 308120Domain d1e3sb_: 1e3s B: [59202]
      3. 308121Domain d1e3sc_: 1e3s C: [59203]
      4. 308122Domain d1e3sd_: 1e3s D: [59204]
        complexed with nad
    2. Domains for 1e3w:
      1. 308123Domain d1e3wa_: 1e3w A: [59207]
      2. 308124Domain d1e3wb_: 1e3w B: [59208]
      3. 308125Domain d1e3wc_: 1e3w C: [59209]
      4. 308126Domain d1e3wd_: 1e3w D: [59210]
        CASP4
        complexed with aae, nad, so4, trs
    3. Domains for 1e6w:
      1. 308115Domain d1e6wa_: 1e6w A: [59326]
      2. 308116Domain d1e6wb_: 1e6w B: [59327]
      3. 308117Domain d1e6wc_: 1e6w C: [59328]
      4. 308118Domain d1e6wd_: 1e6w D: [59329]
        complexed with est, nad
  2. 308127Thermus thermophilus [TaxId:274] [89525] (1 PDB entry)

More info for Protein 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases: