Lineage for Protein: Type II 3-hydroxyacyl-CoA dehydrogenase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

    has additional subdomain(s) that are not in the common domain
  6. 2842839Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species)

Species:

  1. 2842840Human (Homo sapiens) [TaxId:9606] [102152] (2 PDB entries)
    Uniprot Q99714
    1. Domain for 1so8:
    2. Domains for 1u7t:
      1. 2842842Domain d1u7ta_: 1u7t A: [113099]
        complexed with nad, tdt
      2. 2842843Domain d1u7tb_: 1u7t B: [113100]
        complexed with nad, tdt
      3. 2842844Domain d1u7tc_: 1u7t C: [113101]
        complexed with nad, tdt
      4. 2842845Domain d1u7td_: 1u7t D: [113102]
        complexed with nad, tdt
  2. 2842846Norway rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries)
    1. Domains for 1e3s:
      1. 2842855Domain d1e3sa_: 1e3s A: [59201]
        complexed with nad
      2. 2842856Domain d1e3sb_: 1e3s B: [59202]
        complexed with nad
      3. 2842857Domain d1e3sc_: 1e3s C: [59203]
        complexed with nad
      4. 2842858Domain d1e3sd_: 1e3s D: [59204]
        complexed with nad
    2. Domains for 1e3w:
      1. 2842851Domain d1e3wa_: 1e3w A: [59207]
        CASP4
        complexed with aae, nad, so4, trs
      2. 2842852Domain d1e3wb_: 1e3w B: [59208]
        CASP4
        complexed with aae, nad, so4, trs
      3. 2842853Domain d1e3wc_: 1e3w C: [59209]
        CASP4
        complexed with aae, nad, so4, trs
      4. 2842854Domain d1e3wd_: 1e3w D: [59210]
        CASP4
        complexed with aae, nad, so4, trs
    3. Domains for 1e6w:
      1. 2842847Domain d1e6wa_: 1e6w A: [59326]
        complexed with est, nad
      2. 2842848Domain d1e6wb_: 1e6w B: [59327]
        complexed with est, nad
      3. 2842849Domain d1e6wc_: 1e6w C: [59328]
        complexed with est, nad
      4. 2842850Domain d1e6wd_: 1e6w D: [59329]
        complexed with est, nad
  3. 2842859Thermus thermophilus [TaxId:274] [89525] (1 PDB entry)

More info for Protein Type II 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Type II 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases: