![]() | Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
![]() | Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
![]() | Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) ![]() |
![]() | Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
![]() | Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species) |
![]() | Human (Homo sapiens) [TaxId:9606] [102152] (2 PDB entries) Uniprot Q99714 |
![]() | Domain d1so8a_: 1so8 A: [98940] complexed with cl, na |
![]() | Domain d1u7ta_: 1u7t A: [113099] complexed with nad, tdt |
![]() | Domain d1u7tb_: 1u7t B: [113100] complexed with nad, tdt |
![]() | Domain d1u7tc_: 1u7t C: [113101] complexed with nad, tdt |
![]() | Domain d1u7td_: 1u7t D: [113102] complexed with nad, tdt |
![]() | Norway rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries) |
![]() | Domain d1e3sa_: 1e3s A: [59201] complexed with nad |
![]() | Domain d1e3sb_: 1e3s B: [59202] complexed with nad |
![]() | Domain d1e3sc_: 1e3s C: [59203] complexed with nad |
![]() | Domain d1e3sd_: 1e3s D: [59204] complexed with nad |
![]() | Domain d1e3wa_: 1e3w A: [59207] CASP4 complexed with aae, nad, so4, trs |
![]() | Domain d1e3wb_: 1e3w B: [59208] CASP4 complexed with aae, nad, so4, trs |
![]() | Domain d1e3wc_: 1e3w C: [59209] CASP4 complexed with aae, nad, so4, trs |
![]() | Domain d1e3wd_: 1e3w D: [59210] CASP4 complexed with aae, nad, so4, trs |
![]() | Domain d1e6wa_: 1e6w A: [59326] complexed with est, nad |
![]() | Domain d1e6wb_: 1e6w B: [59327] complexed with est, nad |
![]() | Domain d1e6wc_: 1e6w C: [59328] complexed with est, nad |
![]() | Domain d1e6wd_: 1e6w D: [59329] complexed with est, nad |
![]() | Thermus thermophilus [TaxId:274] [89525] (1 PDB entry) |
![]() | Domain d1uaya_: 1uay A: [88390] complexed with adn |
![]() | Domain d1uayb_: 1uay B: [88391] complexed with adn |
Timeline for Protein Type II 3-hydroxyacyl-CoA dehydrogenase from c.2.1.2: Tyrosine-dependent oxidoreductases: