Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
Protein Biliverdin IX beta reductase [63931] (1 species) Histidine in the active site instead of the Tyr-Lys dyad |
Species Human (Homo sapiens) [TaxId:9606] [63932] (8 PDB entries) |
Domain d1hdoa_: 1hdo A: [60965] complexed with nap |
Domain d1he2a_: 1he2 A: [60966] complexed with bla, nap |
Domain d1he3a_: 1he3 A: [60967] complexed with mbv, nap |
Domain d1he4a_: 1he4 A: [60968] complexed with fmn, nap |
Domain d1he5a_: 1he5 A: [60969] complexed with lum, nap |
Domain d5ooga_: 5oog A: [347923] automated match to d1hdoa_ complexed with a0b, gol, nap, po4 |
Domain d5ooha_: 5ooh A: [348563] automated match to d1hdoa_ complexed with 9zz, gol, nap |
Domain d6opla_: 6opl A: [384678] automated match to d1hdoa_ complexed with nap; mutant |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 Biliverdin IX beta reductase: