Lineage for Species: Leishmania major [TaxId: 5664]

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 685975Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 685976Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 686289Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 686542Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 686545Species Leishmania major [TaxId:5664] [63926] (8 PDB entries)

PDB entries in Species: Leishmania major [TaxId: 5664]:

  1. Domain(s) for 1e7w:
    1. 686546Domain d1e7wa_: 1e7w A: [59373]
    2. 686547Domain d1e7wb_: 1e7w B: [59374]
      complexed with edo, mtx, ndp
  2. Domain(s) for 1e92:
    1. 686548Domain d1e92a_: 1e92 A: [64798]
    2. 686549Domain d1e92b_: 1e92 B: [64799]
    3. 686550Domain d1e92c_: 1e92 C: [64800]
    4. 686551Domain d1e92d_: 1e92 D: [64801]
      complexed with edo, hbi, nap
  3. Domain(s) for 1w0c:
    1. 686572Domain d1w0ca_: 1w0c A: [114052]
    2. 686573Domain d1w0cb_: 1w0c B: [114053]
    3. 686574Domain d1w0cc_: 1w0c C: [114054]
    4. 686575Domain d1w0cd_: 1w0c D: [114055]
    5. 686576Domain d1w0ce_: 1w0c E: [114056]
    6. 686577Domain d1w0cf_: 1w0c F: [114057]
    7. 686578Domain d1w0cg_: 1w0c G: [114058]
    8. 686579Domain d1w0ch_: 1w0c H: [114059]
      complexed with nap, taq
  4. Domain(s) for 2bf7:
    1. 686552Domain d2bf7a1: 2bf7 A:6-288 [128407]
      automatically matched to d1e7wa_
      complexed with edo, hbi, nap
    2. 686553Domain d2bf7b1: 2bf7 B:6-288 [128408]
      automatically matched to d1e7wa_
      complexed with edo, hbi, nap
    3. 686554Domain d2bf7c1: 2bf7 C:6-288 [128409]
      automatically matched to d1e7wa_
      complexed with edo, hbi, nap
    4. 686555Domain d2bf7d1: 2bf7 D:6-288 [128410]
      automatically matched to d1e7wa_
      complexed with edo, hbi, nap
  5. Domain(s) for 2bfa:
    1. 686560Domain d2bfaa1: 2bfa A:6-288 [128413]
      automatically matched to d1e7wa_
      complexed with cb3, edo, ndp
    2. 686561Domain d2bfab1: 2bfa B:6-288 [128414]
      automatically matched to d1e7wa_
      complexed with cb3, edo, ndp
    3. 686562Domain d2bfac1: 2bfa C:6-288 [128415]
      automatically matched to d1e7wa_
      complexed with cb3, edo, ndp
    4. 686563Domain d2bfad1: 2bfa D:6-288 [128416]
      automatically matched to d1e7wa_
      complexed with cb3, edo, ndp
  6. Domain(s) for 2bfm:
    1. 686568Domain d2bfma1: 2bfm A:6-288 [128439]
      automatically matched to d1e7wa_
      complexed with ndp, top
    2. 686569Domain d2bfmb1: 2bfm B:6-288 [128440]
      automatically matched to d1e7wa_
      complexed with ndp, top
    3. 686570Domain d2bfmc1: 2bfm C:6-288 [128441]
      automatically matched to d1e7wa_
      complexed with ndp, top
    4. 686571Domain d2bfmd1: 2bfm D:6-288 [128442]
      automatically matched to d1e7wa_
      complexed with ndp, top
  7. Domain(s) for 2bfo:
    1. 686564Domain d2bfoa1: 2bfo A:6-288 [128444]
      automatically matched to d1e7wa_
      complexed with edo, ndp
    2. 686565Domain d2bfob1: 2bfo B:6-288 [128445]
      automatically matched to d1e7wa_
      complexed with edo, ndp
    3. 686566Domain d2bfoc1: 2bfo C:6-288 [128446]
      automatically matched to d1e7wa_
      complexed with edo, ndp
    4. 686567Domain d2bfod1: 2bfo D:6-288 [128447]
      automatically matched to d1e7wa_
      complexed with edo, ndp
  8. Domain(s) for 2bfp:
    1. 686556Domain d2bfpa1: 2bfp A:6-288 [128448]
      automatically matched to d1e7wa_
      complexed with edo, h4b, nap
    2. 686557Domain d2bfpb1: 2bfp B:6-288 [128449]
      automatically matched to d1e7wa_
      complexed with edo, h4b, nap
    3. 686558Domain d2bfpc1: 2bfp C:6-288 [128450]
      automatically matched to d1e7wa_
      complexed with edo, h4b, nap
    4. 686559Domain d2bfpd1: 2bfp D:6-288 [128451]
      automatically matched to d1e7wa_
      complexed with edo, h4b, nap

More info for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):