Lineage for Species: Leishmania major

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 574151Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 574152Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 574451Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (53 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 574630Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 574633Species Leishmania major [TaxId:5664] [63926] (3 PDB entries)

PDB entries in Species: Leishmania major:

  1. Domain(s) for 1e7w:
    1. 574634Domain d1e7wa_: 1e7w A: [59373]
    2. 574635Domain d1e7wb_: 1e7w B: [59374]
      complexed with edo, mtx, ndp
  2. Domain(s) for 1e92:
    1. 574636Domain d1e92a_: 1e92 A: [64798]
    2. 574637Domain d1e92b_: 1e92 B: [64799]
    3. 574638Domain d1e92c_: 1e92 C: [64800]
    4. 574639Domain d1e92d_: 1e92 D: [64801]
      complexed with edo, hbi, nap
  3. Domain(s) for 1w0c:
    1. 574640Domain d1w0ca_: 1w0c A: [114052]
    2. 574641Domain d1w0cb_: 1w0c B: [114053]
    3. 574642Domain d1w0cc_: 1w0c C: [114054]
    4. 574643Domain d1w0cd_: 1w0c D: [114055]
    5. 574644Domain d1w0ce_: 1w0c E: [114056]
    6. 574645Domain d1w0cf_: 1w0c F: [114057]
    7. 574646Domain d1w0cg_: 1w0c G: [114058]
    8. 574647Domain d1w0ch_: 1w0c H: [114059]
      complexed with nap, taq

More info for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):