Lineage for Species: Leishmania major

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 387036Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 387037Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families) (S)
  5. 387288Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (40 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 387409Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 387412Species Leishmania major [TaxId:5664] [63926] (2 PDB entries)

PDB entries in Species: Leishmania major:

  1. Domain(s) for 1e7w:
    1. 387413Domain d1e7wa_: 1e7w A: [59373]
    2. 387414Domain d1e7wb_: 1e7w B: [59374]
      complexed with edo, mtx, ndp
  2. Domain(s) for 1e92:
    1. 387415Domain d1e92a_: 1e92 A: [64798]
    2. 387416Domain d1e92b_: 1e92 B: [64799]
    3. 387417Domain d1e92c_: 1e92 C: [64800]
    4. 387418Domain d1e92d_: 1e92 D: [64801]
      complexed with edo, hbi, nap

More info for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):