Lineage for Species: Leishmania major [TaxId: 5664]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2090925Protein Dihydropteridin reductase (pteridine reductase) [51769] (7 species)
  7. 2090928Species Leishmania major [TaxId:5664] [63926] (13 PDB entries)
    Uniprot Q01782

PDB entries in Species: Leishmania major [TaxId: 5664]:

  1. Domain(s) for 1e7w:
    1. 2090929Domain d1e7wa_: 1e7w A: [59373]
      complexed with edo, mtx, ndp
    2. 2090930Domain d1e7wb_: 1e7w B: [59374]
      complexed with edo, mtx, ndp
  2. Domain(s) for 1e92:
    1. 2090931Domain d1e92a_: 1e92 A: [64798]
      complexed with edo, hbi, nap
    2. 2090932Domain d1e92b_: 1e92 B: [64799]
      complexed with edo, hbi, nap
    3. 2090933Domain d1e92c_: 1e92 C: [64800]
      complexed with edo, hbi, nap
    4. 2090934Domain d1e92d_: 1e92 D: [64801]
      complexed with edo, hbi, nap
  3. Domain(s) for 1w0c:
    1. 2090974Domain d1w0ca_: 1w0c A: [114052]
      complexed with nap, taq
    2. 2090975Domain d1w0cb_: 1w0c B: [114053]
      complexed with nap, taq
    3. 2090976Domain d1w0cc_: 1w0c C: [114054]
      complexed with nap, taq
    4. 2090977Domain d1w0cd_: 1w0c D: [114055]
      complexed with nap, taq
    5. 2090978Domain d1w0ce_: 1w0c E: [114056]
      complexed with nap, taq
    6. 2090979Domain d1w0cf_: 1w0c F: [114057]
      complexed with nap, taq
    7. 2090980Domain d1w0cg_: 1w0c G: [114058]
      complexed with nap, taq
    8. 2090981Domain d1w0ch_: 1w0c H: [114059]
      complexed with nap, taq
  4. Domain(s) for 2bf7:
    1. 2090938Domain d2bf7a_: 2bf7 A: [128407]
      automated match to d1e7wa_
      complexed with edo, hbi, nap
    2. 2090939Domain d2bf7b_: 2bf7 B: [128408]
      automated match to d1e7wa_
      complexed with edo, hbi, nap
    3. 2090940Domain d2bf7c_: 2bf7 C: [128409]
      automated match to d1e7wa_
      complexed with edo, hbi, nap
    4. 2090941Domain d2bf7d_: 2bf7 D: [128410]
      automated match to d1e7wa_
      complexed with edo, hbi, nap
  5. Domain(s) for 2bfa:
    1. 2090950Domain d2bfaa_: 2bfa A: [128413]
      automated match to d1e7wa_
      complexed with cb3, edo, ndp
    2. 2090951Domain d2bfab_: 2bfa B: [128414]
      automated match to d1e7wa_
      complexed with cb3, edo, ndp
    3. 2090952Domain d2bfac_: 2bfa C: [128415]
      automated match to d1e7wa_
      complexed with cb3, edo, ndp
    4. 2090953Domain d2bfad_: 2bfa D: [128416]
      automated match to d1e7wa_
      complexed with cb3, edo, ndp
  6. Domain(s) for 2bfm:
    1. 2090954Domain d2bfma_: 2bfm A: [128439]
      automated match to d1e7wa_
      complexed with ndp, top
    2. 2090955Domain d2bfmb_: 2bfm B: [128440]
      automated match to d1e7wa_
      complexed with ndp, top
    3. 2090956Domain d2bfmc_: 2bfm C: [128441]
      automated match to d1e7wa_
      complexed with ndp, top
    4. 2090957Domain d2bfmd_: 2bfm D: [128442]
      automated match to d1e7wa_
      complexed with ndp, top
  7. Domain(s) for 2bfo:
    1. 2090946Domain d2bfoa_: 2bfo A: [128444]
      automated match to d1e7wa_
      complexed with edo, ndp
    2. 2090947Domain d2bfob_: 2bfo B: [128445]
      automated match to d1e7wa_
      complexed with edo, ndp
    3. 2090948Domain d2bfoc_: 2bfo C: [128446]
      automated match to d1e7wa_
      complexed with edo, ndp
    4. 2090949Domain d2bfod_: 2bfo D: [128447]
      automated match to d1e7wa_
      complexed with edo, ndp
  8. Domain(s) for 2bfp:
    1. 2090942Domain d2bfpa_: 2bfp A: [128448]
      automated match to d1e7wa_
      complexed with edo, h4b, nap
    2. 2090943Domain d2bfpb_: 2bfp B: [128449]
      automated match to d1e7wa_
      complexed with edo, h4b, nap
    3. 2090944Domain d2bfpc_: 2bfp C: [128450]
      automated match to d1e7wa_
      complexed with edo, h4b, nap
    4. 2090945Domain d2bfpd_: 2bfp D: [128451]
      automated match to d1e7wa_
      complexed with edo, h4b, nap
  9. Domain(s) for 2p8k:
    1. 2090958Domain d2p8ka_: 2p8k A: [304331]
      automated match to d1e92b_
      complexed with dyp, nap
    2. 2090959Domain d2p8kb_: 2p8k B: [304332]
      automated match to d1e92b_
      complexed with dyp, nap
    3. 2090960Domain d2p8kc_: 2p8k C: [304333]
      automated match to d1e92a_
      complexed with dyp, nap
    4. 2090961Domain d2p8kd_: 2p8k D: [304334]
      automated match to d1e92b_
      complexed with dyp, nap
    5. 2090962Domain d2p8ke_: 2p8k E: [304335]
      automated match to d1e92a_
      complexed with dyp, nap
    6. 2090963Domain d2p8kf_: 2p8k F: [304336]
      automated match to d1e92b_
      complexed with dyp, nap
    7. 2090964Domain d2p8kg_: 2p8k G: [304337]
      automated match to d1e92a_
      complexed with dyp, nap
    8. 2090965Domain d2p8kh_: 2p8k H: [304338]
      automated match to d1e92b_
      complexed with dyp, nap
  10. Domain(s) for 2qhx:
    1. 2090935Domain d2qhxa1: 2qhx A:5-288 [150796]
      Other proteins in same PDB: d2qhxc_
      automatically matched to d1e7wa_
      complexed with fe1, iod, nap
    2. 2090936Domain d2qhxb1: 2qhx B:5-288 [150797]
      Other proteins in same PDB: d2qhxc_
      automatically matched to d1e7wa_
      complexed with fe1, iod, nap
    3. 2090937Domain d2qhxd1: 2qhx D:5-288 [150799]
      Other proteins in same PDB: d2qhxc_
      automatically matched to d1e7wa_
      complexed with fe1, iod, nap
  11. Domain(s) for 3h4v:
    1. 2090966Domain d3h4va_: 3h4v A: [177181]
      automated match to d1e7wa_
      complexed with dvp, nap
    2. 2090967Domain d3h4vb_: 3h4v B: [177182]
      automated match to d1e7wa_
      complexed with dvp, nap
    3. 2090968Domain d3h4vc_: 3h4v C: [177183]
      automated match to d1e7wa_
      complexed with dvp, nap
    4. 2090969Domain d3h4vd_: 3h4v D: [177184]
      automated match to d1e7wa_
      complexed with dvp, nap
    5. 2090970Domain d3h4ve_: 3h4v E: [177185]
      automated match to d1e7wa_
      complexed with dvp, nap
    6. 2090971Domain d3h4vf_: 3h4v F: [177186]
      automated match to d1e7wa_
      complexed with dvp, nap
    7. 2090972Domain d3h4vg_: 3h4v G: [177187]
      automated match to d1e7wa_
      complexed with dvp, nap
    8. 2090973Domain d3h4vh_: 3h4v H: [177188]
      automated match to d1e7wa_
      complexed with dvp, nap
  12. Domain(s) for 5l42:
    1. 2296237Domain d5l42b_: 5l42 B: [339538]
      automated match to d1e92b_
      complexed with 6j6, act, edo, gol, ndp, pge
    2. 2296251Domain d5l42d_: 5l42 D: [339552]
      automated match to d1e92b_
      complexed with 6j6, act, edo, gol, ndp, pge
    3. 2296254Domain d5l42c_: 5l42 C: [339555]
      automated match to d1e92b_
      complexed with 6j6, act, edo, gol, ndp, pge
    4. 2296279Domain d5l42a_: 5l42 A: [339580]
      automated match to d1e92b_
      complexed with 6j6, act, edo, gol, ndp, pge
  13. Domain(s) for 5l4n:
    1. 2288366Domain d5l4nb_: 5l4n B: [331667]
      automated match to d1e92b_
      complexed with 6qt, act, edo, gol, ndp, peg, pge
    2. 2288371Domain d5l4nd_: 5l4n D: [331672]
      automated match to d1e92b_
      complexed with 6qt, act, edo, gol, ndp, peg, pge
    3. 2288374Domain d5l4na_: 5l4n A: [331675]
      automated match to d1e92b_
      complexed with 6qt, act, edo, gol, ndp, peg, pge
    4. 2288380Domain d5l4nc_: 5l4n C: [331681]
      automated match to d1e92b_
      complexed with 6qt, act, edo, gol, ndp, peg, pge

More info for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Leishmania major [TaxId:5664] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):