Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1815292Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 1821671Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 1822493Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins)
    hybrid of classes I and II aldolase
    automatically mapped to Pfam PF00490
  6. 1822494Protein 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595] (5 species)
  7. 1822515Species Human (Homo sapiens) [TaxId:9606] [63921] (2 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1e51:
    1. 1822518Domain d1e51a_: 1e51 A: [59254]
      complexed with pbg, so4, zn
    2. 1822519Domain d1e51b_: 1e51 B: [59255]
      complexed with pbg, so4, zn
  2. Domain(s) for 1pv8:
    1. 1822516Domain d1pv8a_: 1pv8 A: [95155]
      complexed with pb1, zn; mutant
    2. 1822517Domain d1pv8b_: 1pv8 B: [95156]
      complexed with pb1, zn; mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from c.1.10.3 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.1.10.3 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase):