Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2085156Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2086002Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 protein domains)
    hybrid of classes I and II aldolase
    automatically mapped to Pfam PF00490
  6. 2086003Protein 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595] (5 species)
  7. 2086025Species Human (Homo sapiens) [TaxId:9606] [63921] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1e51:
    1. 2086028Domain d1e51a_: 1e51 A: [59254]
      complexed with pbg, so4, zn
    2. 2086029Domain d1e51b_: 1e51 B: [59255]
      complexed with pbg, so4, zn
  2. Domain(s) for 1pv8:
    1. 2086026Domain d1pv8a_: 1pv8 A: [95155]
      complexed with pb1, zn; mutant
    2. 2086027Domain d1pv8b_: 1pv8 B: [95156]
      complexed with pb1, zn; mutant
  3. Domain(s) for 5hms:
    1. 2271456Domain d5hmsa_: 5hms A: [314757]
      automated match to d1e51a_
      complexed with zn
    2. 2271457Domain d5hmsb_: 5hms B: [314758]
      automated match to d1e51a_
      complexed with zn
  4. Domain(s) for 5hnr:
    1. 2271502Domain d5hnrb_: 5hnr B: [314803]
      automated match to d1e51a_
      complexed with dav, so4, zn
    2. 2271530Domain d5hnra_: 5hnr A: [314831]
      automated match to d1e51a_
      complexed with dav, so4, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.1.10.3 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.1.10.3 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase):