SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: Pdz-RhoGEF RGS-like domain

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2002317Fold a.91: Regulator of G-protein signaling, RGS [48096] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
    contains a 4-helical bundle with left-handed twist and up-and-down topology
  4. 2002318Superfamily a.91.1: Regulator of G-protein signaling, RGS [48097] (2 families) (S)
  5. 2002319Family a.91.1.1: Regulator of G-protein signaling, RGS [48098] (10 protein domains)
  6. 2002341Protein Pdz-RhoGEF RGS-like domain [63586] (1 species)
    contains extra helices in the C-terminal extension

Species:

More info for Protein Pdz-RhoGEF RGS-like domain from a.91.1.1: Regulator of G-protein signaling, RGS

Timeline for Protein Pdz-RhoGEF RGS-like domain from a.91.1.1: Regulator of G-protein signaling, RGS: