SCOPe 2.04: Family a.39.1.8: Penta-EF-hand proteins

Lineage for Family a.39.1.8: Penta-EF-hand proteins

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.8: Penta-EF-hand proteins [63550] (7 proteins)

Proteins:

1. Apoptosis-linked protein alg-2 [63551] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [63552] (1 PDB entry)

2. Calpain large subunit, C-terminal domain (domain IV) [47556] (3 species)

   1. Species Human (Homo sapiens), M-type [TaxId:9606] [47557] (2 PDB entries)

   2. Species Norway rat (Rattus norvegicus), M-type [TaxId:10116] [47558] (2 PDB entries)

   3. Species Norway rat (Rattus norvegicus), mu-type [TaxId:10116] [101186] (1 PDB entry)

3. Calpain small (regulatory) subunit (domain VI) [47552] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [47553] (5 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [47554] (8 PDB entries)

   3. Species Pig (Sus scrofa) [TaxId:9823] [47555] (7 PDB entries)

4. Grancalcin [47550] (1 species)
   Calpain small subunit homologue

   • Species Human (Homo sapiens) [TaxId:9606] [47551] (4 PDB entries)

5. Programmed cell death 6 protein-like protein [116903] (1 species)

   • Species Leishmania major [TaxId:5664] [116904] (1 PDB entry)
     Uniprot Q4QG08 53-234

6. Sorcin [69023] (2 species)

   1. Species Chinese hamster (Cricetulus griseus) [TaxId:10029] [74723] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [69024] (2 PDB entries)

7. automated matches [226948] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [225306] (1 PDB entry)

More info for Family a.39.1.8: Penta-EF-hand proteins

Timeline for Family a.39.1.8: Penta-EF-hand proteins:

• Family a.39.1.8: Penta-EF-hand proteins first appeared in SCOP 1.57
  
• Family a.39.1.8: Penta-EF-hand proteins appears in SCOPe 2.03
  
• Family a.39.1.8: Penta-EF-hand proteins appears in SCOPe 2.05
  
• Family a.39.1.8: Penta-EF-hand proteins appears in the current release, SCOPe 2.08