SCOP 1.75: Family a.4.5.31: DEP domain

Lineage for Family a.4.5.31: DEP domain

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (84 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.31: DEP domain [63483] (4 proteins)
   membrane-binding domain

Proteins:

1. Pleckstrin [101039] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [116790] (2 PDB entries)
      Uniprot P08567 125-219 # structure of the N-terminal PH domain (1-105) is also known ((50741))

   2. Species Mouse (Mus musculus) [TaxId:10090] [101040] (1 PDB entry)

2. Pleckstrin 2 [101041] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [101042] (1 PDB entry)

3. Regulatory domain of epac2, domain 2 [81693] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [81694] (1 PDB entry)

4. Segment polarity protein Dishevelled-1 [63484] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [63485] (1 PDB entry)

More info for Family a.4.5.31: DEP domain

Timeline for Family a.4.5.31: DEP domain:

• Family a.4.5.31: DEP domain first appeared in SCOP 1.57
  
• Family a.4.5.31: DEP domain appears in SCOP 1.73
  
• Family a.4.5.31: DEP domain appears in SCOPe 2.01
  
• Family a.4.5.31: DEP domain appears in the current release, SCOPe 2.08