Class a: All alpha proteins [46456] (202 folds) |
Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (12 superfamilies) core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down |
Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (45 families) contains a small beta-sheet (wing) |
Family a.4.5.28: MarR-like transcriptional regulators [63379] (8 proteins) The N- and C-terminal helical extensions to the common fold form the dimer interface |
Hypothetical protein PH1061 [101014] (1 species) |
Species Archaeon Pyrococcus horikoshii [TaxId:53953] [101015] (1 PDB entry) |
MexR repressor [81686] (1 species) |
Species Pseudomonas aeruginosa [TaxId:287] [81687] (1 PDB entry) |
Multiple antibiotic resistance repressor, MarR [68970] (1 species) |
Species Escherichia coli [TaxId:562] [68971] (1 PDB entry) |
Pleiotropic regulator of virulence genes, SarA [48292] (1 species) closely related to SarR but adopts a different fold; possible experimental artifact? |
Species Staphylococcus aureus [TaxId:1280] [48293] (1 PDB entry) |
Putative transcriptional regulator YusO [101012] (1 species) |
Species Bacillus subtilis [TaxId:1423] [101013] (1 PDB entry) |
Staphylococcal accessory regulator A homolog, SarR [63472] (1 species) |
Species Staphylococcus aureus [TaxId:1280] [63473] (1 PDB entry) |
Staphylococcal accessory regulator A homolog, SarS [88977] (1 species) duplication: tandem repeat of two SarR-like domains assembled together as in the SarR dimer |
Species Staphylococcus aureus [TaxId:1280] [88978] (1 PDB entry) |
Transcriptional regulator SlyA [81688] (1 species) |
Species Enterococcus faecalis [TaxId:1351] [81689] (1 PDB entry) |
Timeline for Family a.4.5.28: MarR-like transcriptional regulators: