Lineage for Family a.4.5.28: MarR-like transcriptional regulators

  1. Root: SCOP 1.65
  2. 275720Class a: All alpha proteins [46456] (179 folds)
  3. 277521Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (12 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 277839Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (36 families) (S)
    contains a small beta-sheet (wing)
  5. 278193Family a.4.5.28: MarR-like transcriptional regulators [63379] (6 proteins)
    The N- and C-terminal helical extensions to the common fold form the dimer interface


  1. 278194MexR repressor [81686] (1 species)
  2. 278204Multiple antibiotic resistance repressor, MarR [68970] (1 species)
  3. 278207Pleiotropic regulator of virulence genes, SarA [48292] (1 species)
    closely related to SarR but adopts a different fold; possible experimental artefact?
  4. 278211Staphylococcal accessory regulator A homolog, SarR [63472] (1 species)
  5. 278215Staphylococcal accessory regulator A homolog, SarS [88977] (1 species)
    duplication: tandem repeat of two SarR-like domains assembled together as in the SarR dimer
  6. 278219Transcriptional regulator SlyA [81688] (1 species)

More info for Family a.4.5.28: MarR-like transcriptional regulators

Timeline for Family a.4.5.28: MarR-like transcriptional regulators: