Lineage for Family a.4.5.28: MarR-like transcriptional regulators

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily a.4.5: 'Winged helix' DNA-binding domain [46785] (86 families) (S)
    contains a small beta-sheet (wing)
  5. Family a.4.5.28: MarR-like transcriptional regulators [63379] (20 proteins)
    The N- and C-terminal helical extensions to the common fold form the dimer interface

Proteins:

  1. Hypothetical protein PH1061 [101014] (1 species)
  2. MexR repressor [81686] (1 species)
  3. Multiple antibiotic resistance repressor, MarR [68970] (1 species)
  4. Organic hydroperoxide resistance transcriptional regulator OhrR [140247] (1 species)
  5. Pleiotropic regulator of virulence genes, SarA [48292] (1 species)
    closely related to SarR but adopts a different fold; possible experimental artifact?
  6. Probable transcriptional regulator PA3067 [140243] (1 species)
  7. Probable transcriptional regulator PA4135 [140245] (1 species)
  8. Protease production regulatory protein Hpr [140251] (1 species)
  9. Putative transcriptional regulator TM0816 [140241] (1 species)
  10. Putative transcriptional regulator YusO [101012] (1 species)
  11. Staphylococcal accessory regulator A homolog, SarR [63472] (1 species)
  12. Staphylococcal accessory regulator A homolog, SarS [88977] (1 species)
    duplication: tandem repeat of two SarR-like domains assembled together as in the SarR dimer
  13. Ta1064 (RFK), N-terminal domain [158274] (1 species)
  14. Transcriptional regulator DR1159 [140255] (1 species)
  15. Transcriptional regulator MgrA [158272] (1 species)
  16. Transcriptional regulator OEOE1854 [158276] (1 species)
  17. Transcriptional regulator PA3341 [140249] (1 species)
  18. Transcriptional regulator SlyA [81688] (2 species)
    1. Species Enterococcus faecalis [TaxId:1351] [81689] (1 PDB entry)
    2. Species Salmonella typhimurium [TaxId:90371] [158271] (3 PDB entries)
      Uniprot P40676 1-140
  19. Transcriptional regulator TM0710 [140253] (1 species)
  20. automated matches [190294] (6 species)
    not a true protein
    1. Species Deinococcus radiodurans [TaxId:1299] [187697] (2 PDB entries)
    2. Species Escherichia coli K-12 [TaxId:83333] [193218] (4 PDB entries)
    3. Species Pseudomonas aeruginosa [TaxId:287] [320186] (1 PDB entry)
    4. Species Staphylococcus aureus [311136] (1 PDB entry)
    5. Species Thermotoga maritima [TaxId:2336] [187380] (1 PDB entry)
    6. Species Yersinia pseudotuberculosis [TaxId:502800] [193529] (1 PDB entry)

More info for Family a.4.5.28: MarR-like transcriptional regulators

Timeline for Family a.4.5.28: MarR-like transcriptional regulators: