Lineage for Family a.4.5.28: MarR-like transcriptional regulators

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2304501Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 2305606Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (86 families) (S)
    contains a small beta-sheet (wing)
  5. 2306333Family a.4.5.28: MarR-like transcriptional regulators [63379] (20 protein domains)
    The N- and C-terminal helical extensions to the common fold form the dimer interface

Protein Domains:

  1. 2306334Hypothetical protein PH1061 [101014] (1 species)
  2. 2306337MexR repressor [81686] (1 species)
  3. 2306351Multiple antibiotic resistance repressor, MarR [68970] (1 species)
  4. 2306354Organic hydroperoxide resistance transcriptional regulator OhrR [140247] (1 species)
  5. 2306363Pleiotropic regulator of virulence genes, SarA [48292] (1 species)
    closely related to SarR but adopts a different fold; possible experimental artifact?
  6. 2306371Probable transcriptional regulator PA3067 [140243] (1 species)
  7. 2306377Probable transcriptional regulator PA4135 [140245] (1 species)
  8. 2306380Protease production regulatory protein Hpr [140251] (1 species)
  9. 2306386Putative transcriptional regulator TM0816 [140241] (1 species)
  10. 2306390Putative transcriptional regulator YusO [101012] (1 species)
  11. 2306394Staphylococcal accessory regulator A homolog, SarR [63472] (1 species)
  12. 2306398Staphylococcal accessory regulator A homolog, SarS [88977] (1 species)
    duplication: tandem repeat of two SarR-like domains assembled together as in the SarR dimer
  13. 2306402Ta1064 (RFK), N-terminal domain [158274] (1 species)
  14. 2306405Transcriptional regulator DR1159 [140255] (1 species)
  15. 2306408Transcriptional regulator MgrA [158272] (1 species)
  16. 2306411Transcriptional regulator OEOE1854 [158276] (1 species)
  17. 2306417Transcriptional regulator PA3341 [140249] (1 species)
  18. 2306420Transcriptional regulator SlyA [81688] (2 species)
    1. 2306421Species Enterococcus faecalis [TaxId:1351] [81689] (1 PDB entry)
    2. 2306424Species Salmonella typhimurium [TaxId:90371] [158271] (3 PDB entries)
      Uniprot P40676 1-140
  19. 2306430Transcriptional regulator TM0710 [140253] (1 species)
  20. 2306433automated matches [190294] (6 species)
    not a true protein
    1. 2306434Species Deinococcus radiodurans [TaxId:1299] [187697] (2 PDB entries)
    2. 2306438Species Escherichia coli K-12 [TaxId:83333] [193218] (4 PDB entries)
    3. 2306447Species Pseudomonas aeruginosa [TaxId:287] [320186] (1 PDB entry)
    4. 2306450Species Staphylococcus aureus [311136] (1 PDB entry)
    5. 2306452Species Thermotoga maritima [TaxId:2336] [187380] (1 PDB entry)
    6. 2306456Species Yersinia pseudotuberculosis [TaxId:502800] [193529] (1 PDB entry)

More info for Family a.4.5.28: MarR-like transcriptional regulators

Timeline for Family a.4.5.28: MarR-like transcriptional regulators: