SCOPe 2.07: Domain d1jtub_: 1jtu B:

Lineage for d1jtub_ (1jtu B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (71 PDB entries)

8. Domain d1jtub_: 1jtu B: [63285]
   complexed with lyb, ump

Details for d1jtub_

PDB Entry: 1jtu, 2.2 Å

PDB Description: E. coli Thymidylate Synthase in a Complex with dUMP and LY338913, A Polyglutamylated Pyrrolo(2,3-d)pyrimidine-based Antifolate

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d1jtub_:

Sequence; same for both SEQRES and ATOM records:

>d1jtub_ d.117.1.1 (B:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d1jtub_:

• d1jtub_ first appeared in SCOP 1.57
  
• d1jtub_ appears in SCOPe 2.06
  
• d1jtub_ appears in the current release, SCOPe 2.08