SCOPe 2.01: Domain d1jbuh_: 1jbu H:

Lineage for d1jbuh_ (1jbu H:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (28 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d1jbuh_: 1jbu H: [62856]
   Other proteins in same PDB: d1jbul_
   complexed with ben, so4

Details for d1jbuh_

PDB Entry: 1jbu, 2 Å

PDB Description: coagulation factor vii zymogen (egf2/protease) in complex with inhibitory exosite peptide a-183

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d1jbuh_:

Sequence, based on SEQRES records:

>d1jbuh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
kvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehdlseh
dgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsertlafv
rfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagysdgs
kdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsepr
pgvllrapfp

Sequence, based on observed residues (ATOM records):

>d1jbuh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
kvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehdhdgd
eqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsertlafvrfs
lvsgwtalelmvlnvprlmtqdclqqsrkvgdspniteymfcagysdgskdsckgdsggp
hathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprpgvllrapfp

Timeline for d1jbuh_:

• d1jbuh_ first appeared in SCOP 1.57
  
• d1jbuh_ appears in SCOP 1.75
  
• d1jbuh_ appears in SCOPe 2.02
  
• d1jbuh_ appears in the current release, SCOPe 2.08