Lineage for d1iqdb2 (1iqd B:115-212)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655115Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 655144Domain d1iqdb2: 1iqd B:115-212 [62647]
    Other proteins in same PDB: d1iqda1, d1iqda2, d1iqdb1, d1iqdc_
    part of Fab BO2C11 against the C2 domain of factor VIII
    mutant

Details for d1iqdb2

PDB Entry: 1iqd (more details), 2 Å

PDB Description: Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
PDB Compounds: (B:) human monoclonal bo2c11 fab heavy chain

SCOP Domain Sequences for d1iqdb2:

Sequence, based on SEQRES records: (download)

>d1iqdb2 b.1.1.2 (B:115-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtatytcnvdhkpsntkvdkrv

Sequence, based on observed residues (ATOM records): (download)

>d1iqdb2 b.1.1.2 (B:115-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplataalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvtatytcnvdhkpsntkvdkrv

SCOP Domain Coordinates for d1iqdb2:

Click to download the PDB-style file with coordinates for d1iqdb2.
(The format of our PDB-style files is described here.)

Timeline for d1iqdb2: