Lineage for d1io4c_ (1io4 C:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2033752Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2034243Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2034595Family b.2.5.6: RUNT domain [81318] (2 protein domains)
    automatically mapped to Pfam PF00853
  6. 2034596Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439] (2 species)
    synonym: core binding factor alpha, cbfa
  7. 2034610Species Mouse (Mus musculus) [TaxId:10090] [63684] (14 PDB entries)
    almost identical sequence to the human protein
  8. 2034631Domain d1io4c_: 1io4 C: [62616]
    Other proteins in same PDB: d1io4a_, d1io4b_, d1io4d_
    protein/DNA complex; complexed with au

Details for d1io4c_

PDB Entry: 1io4 (more details), 3 Å

PDB Description: crystal structure of runx-1/aml1/cbfalpha runt domain-cbfbeta core domain heterodimer and c/ebpbeta bzip homodimer bound to a dna fragment from the csf-1r promoter
PDB Compounds: (C:) runt-related transcription factor 1

SCOPe Domain Sequences for d1io4c_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1io4c_ b.2.5.6 (C:) Acute myeloid leukemia 1 protein (AML1), RUNT domain {Mouse (Mus musculus) [TaxId: 10090]}

SCOPe Domain Coordinates for d1io4c_:

Click to download the PDB-style file with coordinates for d1io4c_.
(The format of our PDB-style files is described here.)

Timeline for d1io4c_: