SCOP 1.67: Domain d1ii4f2: 1ii4 F:251-361

Lineage for d1ii4f2 (1ii4 F:251-361)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (22 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.4: I set domains [49159] (32 proteins)

6. Protein Fibroblast growth factor receptor, FGFR [49179] (4 species)

7. Species Human (Homo sapiens), FGFR2a [TaxId:9606] [49181] (5 PDB entries)

8. Domain d1ii4f2: 1ii4 F:251-361 [62407]
   Other proteins in same PDB: d1ii4a_, d1ii4b_, d1ii4c_, d1ii4d_

Details for d1ii4f2

PDB Entry: 1ii4, 2.7 Å

PDB Description: crystal structure of ser252trp apert mutant fgf receptor 2 (fgfr2) in complex with fgf2

SCOP Domain Sequences for d1ii4f2:

Sequence, based on SEQRES records:

>d1ii4f2 b.1.1.4 (F:251-361) Fibroblast growth factor receptor, FGFR {Human (Homo sapiens), FGFR2a}
rwphrpilqaglpanastvvggdvefvckvysdaqphiqwikhvekngskygpdglpylk
vlkaagvnttdkeievlyirnvtfedageytclagnsigisfhsawltvlp

Sequence, based on observed residues (ATOM records):

>d1ii4f2 b.1.1.4 (F:251-361) Fibroblast growth factor receptor, FGFR {Human (Homo sapiens), FGFR2a}
rwphrpilqaglpanastvvggdvefvckvysdaqphiqwikhvpylkvlkaagvnttdk
eievlyirnvtfedageytclagnsigisfhsawltvlp

Timeline for d1ii4f2:

• d1ii4f2 first appeared in SCOP 1.57
  
• d1ii4f2 appears in SCOP 1.65
  
• d1ii4f2 appears in SCOP 1.69
  
• d1ii4f2 appears in the current release, SCOPe 2.08