Lineage for d1icia1 (1ici A:1-245)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2121033Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2121034Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2121318Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2121332Protein AF1676, Sir2 homolog (Sir2-AF1?) [63985] (1 species)
  7. 2121333Species Archaeoglobus fulgidus [TaxId:2234] [63986] (6 PDB entries)
  8. 2121338Domain d1icia1: 1ici A:1-245 [62266]
    Other proteins in same PDB: d1icia2
    complexed with nad, zn

Details for d1icia1

PDB Entry: 1ici (more details), 2.1 Å

PDB Description: crystal structure of a sir2 homolog-nad complex
PDB Compounds: (A:) Transcriptional regulatory protein, Sir2 family

SCOPe Domain Sequences for d1icia1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1icia1 c.31.1.5 (A:1-245) AF1676, Sir2 homolog (Sir2-AF1?) {Archaeoglobus fulgidus [TaxId: 2234]}

SCOPe Domain Coordinates for d1icia1:

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Timeline for d1icia1:

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