SCOP 1.65: Domain d1i7zc2: 1i7z C:108-214

Lineage for d1i7zc2 (1i7z C:108-214)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (22 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (62 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)

8. Domain d1i7zc2: 1i7z C:108-214 [61924]
   Other proteins in same PDB: d1i7za1, d1i7zb1, d1i7zb2, d1i7zc1, d1i7zd1, d1i7zd2
   part of humanized Fab GNC92H2
   complexed with coc

Details for d1i7zc2

PDB Entry: 1i7z, 2.3 Å

PDB Description: antibody gnc92h2 bound to ligand

SCOP Domain Sequences for d1i7zc2:

Sequence; same for both SEQRES and ATOM records:

>d1i7zc2 b.1.1.2 (C:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d1i7zc2:

• d1i7zc2 first appeared in SCOP 1.57
  
• d1i7zc2 appears in SCOP 1.63
  
• d1i7zc2 appears in SCOP 1.67
  
• d1i7zc2 appears in the current release, SCOPe 2.08