SCOP 1.65: Domain d1i7zb2: 1i7z B:114-228

Lineage for d1i7zb2 (1i7z B:114-228)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (22 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88575] (63 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)

8. Domain d1i7zb2: 1i7z B:114-228 [61922]
   Other proteins in same PDB: d1i7za1, d1i7za2, d1i7zb1, d1i7zc1, d1i7zc2, d1i7zd1

Details for d1i7zb2

PDB Entry: 1i7z, 2.3 Å

PDB Description: antibody gnc92h2 bound to ligand

SCOP Domain Sequences for d1i7zb2:

Sequence; same for both SEQRES and ATOM records:

>d1i7zb2 b.1.1.2 (B:114-228) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens)}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

Timeline for d1i7zb2:

• d1i7zb2 first appeared in SCOP 1.57
  
• d1i7zb2 appears in SCOP 1.63
  
• d1i7zb2 appears in SCOP 1.67
  
• d1i7zb2 appears in the current release, SCOPe 2.08