Lineage for d1i7za2 (1i7z A:108-214)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2344609Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2348364Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2351429Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 2351430Species Human (Homo sapiens) [TaxId:9606] [88569] (148 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 2351489Domain d1i7za2: 1i7z A:108-214 [61920]
    Other proteins in same PDB: d1i7za1, d1i7zb1, d1i7zb2, d1i7zb3, d1i7zc1, d1i7zd1, d1i7zd2, d1i7zd3
    part of humanized Fab GNC92H2
    complexed with coc

Details for d1i7za2

PDB Entry: 1i7z (more details), 2.3 Å

PDB Description: antibody gnc92h2 bound to ligand
PDB Compounds: (A:) chimera of ig kappa chain: human constant region and mouse variable region

SCOPe Domain Sequences for d1i7za2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1i7za2 b.1.1.2 (A:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOPe Domain Coordinates for d1i7za2:

Click to download the PDB-style file with coordinates for d1i7za2.
(The format of our PDB-style files is described here.)

Timeline for d1i7za2: