SCOPe 2.01: Domain d1i7m.2: 1i7m D:,C:

Lineage for d1i7m.2 (1i7m D:,C:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.156: S-adenosylmethionine decarboxylase [56275] (1 superfamily)
   duplication of beta-alpha-beta(4)-alpha-beta-alpha-beta(2) motif; 4 layers a/b/b/a; antiparallel beta-sheets: order 23451687

4. Superfamily d.156.1: S-adenosylmethionine decarboxylase [56276] (3 families)

5. Family d.156.1.1: S-adenosylmethionine decarboxylase [56277] (1 protein)

6. Protein S-adenosylmethionine decarboxylase [56278] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56279] (8 PDB entries)

8. Domain d1i7m.2: 1i7m D:,C: [61892]
   complexed with cg, put

Details for d1i7m.2

PDB Entry: 1i7m, 2.24 Å

PDB Description: human s-adenosylmethionine decarboxylase with covalently bound pyruvoyl group and complexed with 4-amidinoindan-1-one-2'- amidinohydrazone

PDB Compounds: (C:) s-adenosylmethionine decarboxylase alpha chain, (D:) s-adenosylmethionine decarboxylase beta chain

SCOPe Domain Sequences for d1i7m.2:

Sequence, based on SEQRES records:

>g1i7m.2 d.156.1.1 (D:,C:) S-adenosylmethionine decarboxylase {Human (Homo sapiens) [TaxId: 9606]}
hffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayv
lseXxsmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshq
gyphrnfqeeieflnaifpngagycmgrmnsdcwylytldfpesrvisqpdqtleilmse
ldpavmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtih
itpepefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqkie
gfkrldcqsamfndynfvftsfakkq

Sequence, based on observed residues (ATOM records):

>g1i7m.2 d.156.1.1 (D:,C:) S-adenosylmethionine decarboxylase {Human (Homo sapiens) [TaxId: 9606]}
hffegtekllevwfsgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvlseXxsmf
vskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyphrnfq
eeieflnaifpngagycmgrmnsdcwylytldfqpdqtleilmseldpavmdqfymkdgv
takdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpepefsyvsfetn
lsqtsyddlirkvvevfkpgkfvttlfvnqsskcpqkiegfkrldcqsamfndynfvfts
fakkq

Timeline for d1i7m.2:

• d1i7m.2 first appeared in SCOP 1.57
  
• d1i7m.2 appears in SCOP 1.75
  
• d1i7m.2 appears in SCOPe 2.02
  
• d1i7m.2 appears in the current release, SCOPe 2.08