SCOPe 2.08: Domain d1i7c.1: 1i7c B:,A:

Lineage for d1i7c.1 (1i7c B:,A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.156: S-adenosylmethionine decarboxylase [56275] (1 superfamily)
   duplication of beta-alpha-beta(4)-alpha-beta-alpha-beta(2) motif; 4 layers a/b/b/a; antiparallel beta-sheets: order 23451687

4. Superfamily d.156.1: S-adenosylmethionine decarboxylase [56276] (3 families)

5. Family d.156.1.1: S-adenosylmethionine decarboxylase [56277] (1 protein)
   automatically mapped to Pfam PF01536

6. Protein S-adenosylmethionine decarboxylase [56278] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56279] (8 PDB entries)

8. Domain d1i7c.1: 1i7c B:,A: [61885]
   complexed with mgb, put

Details for d1i7c.1

PDB Entry: 1i7c, 2.4 Å

PDB Description: human s-adenosylmethionine decarboxylase with covalently bound pyruvoyl group and complexed with methylglyoxal bis-(guanylhydrazone)

PDB Compounds: (A:) s-adenosylmethionine decarboxylase alpha chain, (B:) s-adenosylmethionine decarboxylase beta chain

SCOPe Domain Sequences for d1i7c.1:

Sequence, based on SEQRES records:

>g1i7c.1 d.156.1.1 (B:,A:) S-adenosylmethionine decarboxylase {Human (Homo sapiens) [TaxId: 9606]}
ahffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkqeay
vlseXxsmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpsh
qgyphrnfqeeieflnaifpngagycmgrmnsdcwylytldfpesrvisqpdqtleilms
eldpavmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywti
hitpepefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqki
egfkrldcqsamfndynfvftsfakkq

Sequence, based on observed residues (ATOM records):

>g1i7c.1 d.156.1.1 (B:,A:) S-adenosylmethionine decarboxylase {Human (Homo sapiens) [TaxId: 9606]}
ahffegtekllevwfsrqqpqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvls
eXxsmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgy
phrnfqeeieflnaifpngagycmgrmnsdcwylytldfpesrvisqpdqtleilmseld
pavmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihit
pepefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqstvlaspqkiegfkrld
cqsamfndynfvftsfakkq

Timeline for d1i7c.1:

• d1i7c.1 first appeared in SCOP 1.57
  
• d1i7c.1 appears in SCOPe 2.07