SCOPe 2.07: Domain d1i4lb_: 1i4l B:

Lineage for d1i4lb_ (1i4l B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.238: BAR/IMD domain-like [116747] (1 superfamily)
   6 helices, homodimer of 3-helical domains

4. Superfamily a.238.1: BAR/IMD domain-like [103657] (5 families)
   core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends

5. Family a.238.1.2: Arfaptin, Rac-binding fragment [64599] (2 proteins)
   automatically mapped to Pfam PF06456

6. Protein Arfaptin, Rac-binding fragment [64600] (1 species)
   active form is a dimer

7. Species Human (Homo sapiens) [TaxId:9606] [64601] (4 PDB entries)

8. Domain d1i4lb_: 1i4l B: [61719]
   Other proteins in same PDB: d1i4ld_
   complexed with gdp, mg

Details for d1i4lb_

PDB Entry: 1i4l, 2.7 Å

PDB Description: crystal structure analysis of rac1-gdp in complex with arfaptin (p41)

PDB Compounds: (B:) arfaptin 2

SCOPe Domain Sequences for d1i4lb_:

Sequence, based on SEQRES records:

>d1i4lb_ a.238.1.2 (B:) Arfaptin, Rac-binding fragment {Human (Homo sapiens) [TaxId: 9606]}
dlelelqiellretkrkyesvlqlgraltahlysllqtqhalgdafadlsqkspelqeef
gynaetqkllckngetllgavnffvssintlvtktmedtlmtvkqyeaarleydayrtdl
eelslgprdagtrgrlesaqatfqahrdkyeklrgdvaiklkfleenkikvmhkqlllfh
navsayfagnqkqleqt

Sequence, based on observed residues (ATOM records):

>d1i4lb_ a.238.1.2 (B:) Arfaptin, Rac-binding fragment {Human (Homo sapiens) [TaxId: 9606]}
dlelelqiellretkrkyesvlqlgraltahlysllqtqhalgdafadlsqkspelqeef
gynaetqkllckngetllgavnffvssintlvtktmedtlmtvkqyeaarleydayrtdl
eelslgprdkyeklrgdvaiklkfleenkikvmhkqlllfhnavsayfagnqkqleqt

Timeline for d1i4lb_:

• d1i4lb_ first appeared in SCOP 1.57
  
• d1i4lb_ appears in SCOPe 2.06
  
• d1i4lb_ appears in the current release, SCOPe 2.08