SCOP 1.67: Domain d1i2md_: 1i2m D:

Lineage for d1i2md_ (1i2m D:)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.69: 7-bladed beta-propeller [50964] (12 superfamilies)
   consists of seven 4-stranded beta-sheet motifs; meander

4. Superfamily b.69.5: RCC1/BLIP-II [50985] (2 families)
   two families are clearly related but differ by the number of strands per blade

5. Family b.69.5.1: Regulator of chromosome condensation RCC1 [50986] (1 protein)

6. Protein Regulator of chromosome condensation RCC1 [50987] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50988] (2 PDB entries)

8. Domain d1i2md_: 1i2m D: [61571]
   Other proteins in same PDB: d1i2ma_, d1i2mc_
   complexed to Ran
   complexed with so4

Details for d1i2md_

PDB Entry: 1i2m, 1.76 Å

PDB Description: ran-rcc1-so4 complex

SCOP Domain Sequences for d1i2md_:

Sequence, based on SEQRES records:

>d1i2md_ b.69.5.1 (D:) Regulator of chromosome condensation RCC1 {Human (Homo sapiens)}
kvshrshstepglvltlgqgdvgqlglgenvmerkkpalvsipedvvqaeaggmhtvcls
ksgqvysfgcndegalgrdtsvegsemvpgkvelqekvvqvsagdshtaaltddgrvflw
gsfrdnngvigllepmkksmvpvqvqldvpvvkvasgndhlvmltadgdlytlgcgeqgq
lgrvpelfanrggrqglerllvpkcvmlksrgsrghvrfqdafcgayftfaisheghvyg
fglsnyhqlgtpgtescfipqnltsfknstkswvgfsggqhhtvcmdsegkayslgraey
grlglgegaeeksiptlisrlpavssvacgasvgyavtkdgrvfawgmgtnyqlgtgqde
dawspvemmgkqlenrvvlsvssggqhtvllvkdke

Sequence, based on observed residues (ATOM records):

>d1i2md_ b.69.5.1 (D:) Regulator of chromosome condensation RCC1 {Human (Homo sapiens)}
kvshrshstepglvltlgqgdvgqlglgenvmerkkpalvsipedvvqaeaggmhtvcls
ksgqvysfgcndegalgrdtsvegsemvpgkvelqekvvqvsagdshtaaltddgrvflw
gsfrdnngvigllepmkksmvpvqvqldvpvvkvasgndhlvmltadgdlytlgcgeqgq
lgrvpelfanrggrqglerllvpkcvmlkhvrfqdafcgayftfaisheghvygfglsny
hqlgtpgtescfipqnltsfknstkswvgfsggqhhtvcmdsegkayslgraeygrlglg
egaeeksiptlisrlpavssvacgasvgyavtkdgrvfawgmgtnyqlgtgqdedawspv
emmgkqlenrvvlsvssggqhtvllvkdke

Timeline for d1i2md_:

• d1i2md_ first appeared in SCOP 1.57
  
• d1i2md_ appears in SCOP 1.65
  
• d1i2md_ appears in SCOP 1.69
  
• d1i2md_ appears in the current release, SCOPe 2.08