SCOPe 2.08: Domain d1i10a2: 1i10 A:160-331

Lineage for d1i10a2 (1i10 A:160-331)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (20 species)

7. Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (39 PDB entries)

8. Domain d1i10a2: 1i10 A:160-331 [61500]
   Other proteins in same PDB: d1i10a1, d1i10b1, d1i10c1, d1i10d1, d1i10e1, d1i10f1, d1i10g1, d1i10h1
   complexed with act, nai, oxm

Details for d1i10a2

PDB Entry: 1i10, 2.3 Å

PDB Description: human muscle l-lactate dehydrogenase m chain, ternary complex with nadh and oxamate

PDB Compounds: (A:) l-lactate dehydrogenase m chain

SCOPe Domain Sequences for d1i10a2:

Sequence; same for both SEQRES and ATOM records:

>d1i10a2 d.162.1.1 (A:160-331) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
sgcnldsarfrylmgerlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgt
dkdkeqwkevhkqvvesayeviklkgytswaiglsvadlaesimknlrrvhpvstmikgl
ygikddvflsvpcilgqngisdlvkvtltseeearlkksadtlwgiqkelqf

Timeline for d1i10a2:

• d1i10a2 first appeared in SCOP 1.57
  
• d1i10a2 appears in SCOPe 2.07