SCOPe 2.07: Domain d1hzwb_: 1hzw B:

Lineage for d1hzwb_ (1hzw B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55840] (42 PDB entries)

8. Domain d1hzwb_: 1hzw B: [61465]
   complexed with po4

Details for d1hzwb_

PDB Entry: 1hzw, 2 Å

PDB Description: crystal structure of human thymidylate synthase

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d1hzwb_:

Sequence; same for both SEQRES and ATOM records:

>d1hzwb_ d.117.1.1 (B:) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
gselqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvlee
llwfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgaeyr
dmesdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvnse
lscqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhieplki
qlqreprpfpklrilrkvekiddfkaedfqiegynphpt

Timeline for d1hzwb_:

• d1hzwb_ first appeared in SCOP 1.57
  
• d1hzwb_ appears in SCOPe 2.06
  
• d1hzwb_ appears in the current release, SCOPe 2.08