SCOPe 2.05: Domain d1hzwa_: 1hzw A:

Lineage for d1hzwa_ (1hzw A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55840] (24 PDB entries)

8. Domain d1hzwa_: 1hzw A: [61464]
   complexed with po4

Details for d1hzwa_

PDB Entry: 1hzw, 2 Å

PDB Description: crystal structure of human thymidylate synthase

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1hzwa_:

Sequence; same for both SEQRES and ATOM records:

>d1hzwa_ d.117.1.1 (A:) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
gselqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvlee
llwfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgaeyr
dmesdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvnse
lscqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhieplki
qlqreprpfpklrilrkvekiddfkaedfqiegynphpti

Timeline for d1hzwa_:

• d1hzwa_ first appeared in SCOP 1.57
  
• d1hzwa_ appears in SCOPe 2.04
  
• d1hzwa_ appears in SCOPe 2.06
  
• d1hzwa_ appears in the current release, SCOPe 2.08