SCOP 1.73: Domain d1hzwa_: 1hzw A:

Lineage for d1hzwa_ (1hzw A:)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family)

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55840] (5 PDB entries)

8. Domain d1hzwa_: 1hzw A: [61464]

Details for d1hzwa_

PDB Entry: 1hzw, 2 Å

PDB Description: crystal structure of human thymidylate synthase

PDB Compounds: (A:) Thymidylate synthase

SCOP Domain Sequences for d1hzwa_:

Sequence; same for both SEQRES and ATOM records:

>d1hzwa_ d.117.1.1 (A:) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
gselqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvlee
llwfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgaeyr
dmesdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvnse
lscqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhieplki
qlqreprpfpklrilrkvekiddfkaedfqiegynphpti

Timeline for d1hzwa_:

• d1hzwa_ first appeared in SCOP 1.57
  
• d1hzwa_ appears in SCOP 1.71
  
• d1hzwa_ appears in SCOP 1.75
  
• d1hzwa_ appears in the current release, SCOPe 2.08