SCOPe 2.08: Domain d1hygb1: 1hyg B:1-145

Lineage for d1hygb1 (1hyg B:1-145)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)

6. Protein MJ0490, lactate/malate dehydrogenase [63941] (1 species)

7. Species Methanococcus jannaschii [TaxId:2190] [63942] (2 PDB entries)

8. Domain d1hygb1: 1hyg B:1-145 [61404]
   Other proteins in same PDB: d1hyga2, d1hygb2
   complexed with nap

Details for d1hygb1

PDB Entry: 1hyg, 2.8 Å

PDB Description: Crystal structure of MJ0490 gene product, the family of lactate/malate dehydrogenase

PDB Compounds: (B:) l-lactate/malate dehydrogenase

SCOPe Domain Sequences for d1hygb1:

Sequence; same for both SEQRES and ATOM records:

>d1hygb1 c.2.1.5 (B:1-145) MJ0490, lactate/malate dehydrogenase {Methanococcus jannaschii [TaxId: 2190]}
mkvtiigasgrvgsatalllakepfmkdlvligrehsinkleglrediydalagtrsdan
iyvesdenlriidesdvviitsgvprkegmsrmdlaktnakivgkyakkiaeicdtkifv
itnpvdvmtykalvdskfernqvfg

Timeline for d1hygb1:

• d1hygb1 first appeared in SCOP 1.57
  
• d1hygb1 appears in SCOPe 2.07