SCOPe 2.01: Domain d1hxda3: 1hxd A:64-270

Lineage for d1hxda3 (1hxd A:64-270)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.104: Class II aaRS and biotin synthetases [55680] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.104.1: Class II aaRS and biotin synthetases [55681] (4 families)

5. Family d.104.1.2: Biotin holoenzyme synthetase [55707] (2 proteins)

6. Protein Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain [55708] (1 species)
   this structure contains an SH2-like fold

7. Species Escherichia coli [TaxId:562] [55709] (4 PDB entries)

8. Domain d1hxda3: 1hxd A:64-270 [61362]
   Other proteins in same PDB: d1hxda1, d1hxda2, d1hxdb1, d1hxdb2
   complexed with biotin
   complexed with btn

Details for d1hxda3

PDB Entry: 1hxd, 2.4 Å

PDB Description: crystal structure of e. coli biotin repressor with bound biotin

PDB Compounds: (A:) BirA BIFUNCTIONAL PROTEIN

SCOPe Domain Sequences for d1hxda3:

Sequence, based on SEQRES records:

>d1hxda3 d.104.1.2 (A:64-270) Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain {Escherichia coli [TaxId: 562]}
iqllnakqilgqldggsvavlpvidstnqylldrigelksgdaciaeyqqagrgrrgrkw
fspfganlylsmfwrleqgpaaaiglslvigivmaevlrklgadkvrvkwpndlylqdrk
lagilveltgktgdaaqivigaginmamrrveesvvnqgwitlqeaginldrntlaamli
relraalelfeqeglapylsrwekldn

Sequence, based on observed residues (ATOM records):

>d1hxda3 d.104.1.2 (A:64-270) Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain {Escherichia coli [TaxId: 562]}
iqllnakqilgqldggsvavlpvidstnqylldrigelksgdaciaeyqqagrgrrgrkw
fspfganlylsmfwrleqgpaaaiglslvigivmaevlrklgadkvrvkwpndlylqdrk
lagilveltgktgdaaqivigaginmamqgwitlqeaginldrntlaamlirelraalel
feqeglapylsrwekldn

Timeline for d1hxda3:

• d1hxda3 first appeared in SCOP 1.57
  
• d1hxda3 appears in SCOP 1.75
  
• d1hxda3 appears in SCOPe 2.02
  
• d1hxda3 appears in the current release, SCOPe 2.08